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Therapy-Induced Senescence Enhances the Efficacy of HER2-Targeted Antibody-Drug Conjugates in Breast Cancer.
Cancer Res. 2022 Dec 16;82(24):4670-4679. doi: 10.1158/0008-5472.CAN-22-0787.
Cancer Res. 2022.
PMID: 36222720
Free PMC article.
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2.
Chaib S, López-Domínguez JA, Lalinde-Gutiérrez M, Prats N, Marin I, Boix O, García-Garijo A, Meyer K, Muñoz MI, Aguilera M, Mateo L, Stephan-Otto Attolini C, Llanos S, Pérez-Ramos S, Escorihuela M, Al-Shahrour F, Cash TP, Tchkonia T, Kirkland JL, Abad M, Gros A, Arribas J, Serrano M.
Chaib S, et al. Among authors: lalinde gutierrez m.
Nat Cancer. 2024 Mar;5(3):448-462. doi: 10.1038/s43018-023-00712-x. Epub 2024 Jan 24.
Nat Cancer. 2024.
PMID: 38267628
Free PMC article.
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