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Deficiency in nebulin repeats of sarcomeric nebulette is detrimental for cardiomyocyte tolerance to exercise and biomechanical stress.
Vejandla RM, Orgil BO, Alberson NR, Li N, Munkhsaikhan U, Khuchua Z, Martherus R, Azeloglu EU, Xu F, Lu L, Towbin JA, Purevjav E. Vejandla RM, et al. Among authors: martherus r. Am J Physiol Heart Circ Physiol. 2021 May 1;320(5):H2130-H2146. doi: 10.1152/ajpheart.00732.2020. Epub 2021 Apr 16. Am J Physiol Heart Circ Physiol. 2021. PMID: 33861145 Free PMC article.
Disturbance in Z-disk mechanosensitive proteins induced by a persistent mutant myopalladin causes familial restrictive cardiomyopathy.
Huby AC, Mendsaikhan U, Takagi K, Martherus R, Wansapura J, Gong N, Osinska H, James JF, Kramer K, Saito K, Robbins J, Khuchua Z, Towbin JA, Purevjav E. Huby AC, et al. Among authors: martherus r. J Am Coll Cardiol. 2014 Dec 30;64(25):2765-76. doi: 10.1016/j.jacc.2014.09.071. J Am Coll Cardiol. 2014. PMID: 25541130 Free PMC article.
Accelerated cardiac remodeling in desmoplakin transgenic mice in response to endurance exercise is associated with perturbed Wnt/β-catenin signaling.
Martherus R, Jain R, Takagi K, Mendsaikhan U, Turdi S, Osinska H, James JF, Kramer K, Purevjav E, Towbin JA. Martherus R, et al. Am J Physiol Heart Circ Physiol. 2016 Jan 15;310(2):H174-87. doi: 10.1152/ajpheart.00295.2015. Epub 2015 Nov 6. Am J Physiol Heart Circ Physiol. 2016. PMID: 26545710 Free PMC article.
14 results