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Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters.
van Gils N, Verhagen HJMP, Broux M, Martiáñez T, Denkers F, Vermue E, Rutten A, Csikós T, Demeyer S, Çil M, Al M, Cools J, Janssen JJWM, Ossenkoppele GJ, Menezes RX, Smit L. van Gils N, et al. Among authors: martianez t. iScience. 2022 Aug 25;25(9):105013. doi: 10.1016/j.isci.2022.105013. eCollection 2022 Sep 16. iScience. 2022. PMID: 36097617 Free PMC article.
IGFBP7 Induces Differentiation and Loss of Survival of Human Acute Myeloid Leukemia Stem Cells without Affecting Normal Hematopoiesis.
Verhagen HJMP, van Gils N, Martiañez T, van Rhenen A, Rutten A, Denkers F, de Leeuw DC, Smit MA, Tsui ML, de Vos Klootwijk LLE, Menezes RX, Çil M, Roemer MGM, Vermue E, Heukelom S, Zweegman S, Janssen JJWM, Ossenkoppele GJ, Schuurhuis GJ, Smit L. Verhagen HJMP, et al. Among authors: martianez t. Cell Rep. 2018 Dec 11;25(11):3021-3035.e5. doi: 10.1016/j.celrep.2018.11.062. Cell Rep. 2018. PMID: 30540936 Free article.
Constitutively active GSK3β as a means to bolster dendritic cell functionality in the face of tumour-mediated immune suppression.
López González M, Oosterhoff D, Lindenberg JJ, Milenova I, Lougheed SM, Martiáñez T, Dekker H, Quixabeira DCA, Hangalapura B, Joore J, Piersma SR, Cervera-Carrascon V, Santos JM, Scheper RJ, Verheul HMW, Jiménez CR, Van De Ven R, Hemminki A, Van Beusechem VW, De Gruijl TD. López González M, et al. Among authors: martianez t. Oncoimmunology. 2019 Jul 19;8(10):e1631119. doi: 10.1080/2162402X.2019.1631119. eCollection 2019. Oncoimmunology. 2019. PMID: 31646076 Free PMC article.
N-cadherin expression is regulated by UTP in schwannoma cells.
Martiáñez T, Lamarca A, Casals N, Gella A. Martiáñez T, et al. Purinergic Signal. 2013 Jun;9(2):259-70. doi: 10.1007/s11302-012-9348-x. Epub 2012 Dec 28. Purinergic Signal. 2013. PMID: 23271561 Free PMC article.
Generation of digital responses in stress sensors.
Martiáñez T, Francès S, López JM. Martiáñez T, et al. J Biol Chem. 2009 Sep 4;284(36):23902-11. doi: 10.1074/jbc.M109.026054. Epub 2009 Jul 1. J Biol Chem. 2009. PMID: 19570986 Free PMC article.