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Evidence that GPVI is Expressed as a Mixture of Monomers and Dimers, and that the D2 Domain is not Essential for GPVI Activation.
Clark JC, Neagoe RAI, Zuidscherwoude M, Kavanagh DM, Slater A, Martin EM, Soave M, Stegner D, Nieswandt B, Poulter NS, Hummert J, Herten DP, Tomlinson MG, Hill SJ, Watson SP. Clark JC, et al. Among authors: martin em. Thromb Haemost. 2021 Nov;121(11):1435-1447. doi: 10.1055/a-1401-5014. Epub 2021 Apr 14. Thromb Haemost. 2021. PMID: 33638140
Does fibrin(ogen) bind to monomeric or dimeric GPVI, or not at all?
Slater A, Perrella G, Onselaer MB, Martin EM, Gauer JS, Xu RG, Heemskerk JW, Ariëns RAS, Watson SP. Slater A, et al. Among authors: martin em. Platelets. 2019;30(3):281-289. doi: 10.1080/09537104.2018.1508649. Epub 2018 Aug 15. Platelets. 2019. PMID: 30110193
Katacine Is a New Ligand of CLEC-2 that Acts as a Platelet Agonist.
Morán LA, Di Y, Sowa MA, Hermida-Nogueira L, Barrachina MN, Martin E, Clark JC, Mize TH, Eble JA, Moreira D, Pollitt AY, Loza MI, Domínguez E, Watson SP, García Á. Morán LA, et al. Thromb Haemost. 2022 Aug;122(8):1361-1368. doi: 10.1055/a-1772-1069. Epub 2022 Feb 15. Thromb Haemost. 2022. PMID: 35170009 Free PMC article.
Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins.
Maqsood Z, Clark JC, Martin EM, Cheung YFH, Morán LA, Watson SET, Pike JA, Di Y, Poulter NS, Slater A, Lange BMH, Nieswandt B, Eble JA, Tomlinson MG, Owen DM, Stegner D, Bridge LJ, Wierling C, Watson SP. Maqsood Z, et al. Among authors: martin em. PLoS Comput Biol. 2022 Nov 28;18(11):e1010708. doi: 10.1371/journal.pcbi.1010708. eCollection 2022 Nov. PLoS Comput Biol. 2022. PMID: 36441766 Free PMC article.
Heparin and heparin proteoglycan-mimetics activate platelets via PEAR1 and PI3Kβ.
Kardeby C, Evans A, Campos J, Al-Wahaibi AM, Smith CW, Slater A, Martin EM, Severin S, Brill A, Pejler G, Sun Y, Watson SP. Kardeby C, et al. Among authors: martin em. J Thromb Haemost. 2023 Jan;21(1):101-116. doi: 10.1016/j.jtha.2022.10.008. Epub 2022 Dec 22. J Thromb Haemost. 2023. PMID: 36695374 Free article.
306 results