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The dichotomous role of epiregulin in pain.
Verma V, Khoury S, Parisien M, Cho C, Maixner W, Martin LJ, Diatchenko L. Verma V, et al. Among authors: martin lj. Pain. 2020 May;161(5):1052-1064. doi: 10.1097/j.pain.0000000000001792. Pain. 2020. PMID: 31917773 Free PMC article.
The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors.
Wieskopf JS, Mathur J, Limapichat W, Post MR, Al-Qazzaz M, Sorge RE, Martin LJ, Zaykin DV, Smith SB, Freitas K, Austin JS, Dai F, Zhang J, Marcovitz J, Tuttle AH, Slepian PM, Clarke S, Drenan RM, Janes J, Al Sharari S, Segall SK, Aasvang EK, Lai W, Bittner R, Richards CI, Slade GD, Kehlet H, Walker J, Maskos U, Changeux JP, Devor M, Maixner W, Diatchenko L, Belfer I, Dougherty DA, Su AI, Lummis SC, Imad Damaj M, Lester HA, Patapoutian A, Mogil JS. Wieskopf JS, et al. Among authors: martin lj. Sci Transl Med. 2015 May 13;7(287):287ra72. doi: 10.1126/scitranslmed.3009986. Sci Transl Med. 2015. PMID: 25972004 Free PMC article.
Epiregulin and EGFR interactions are involved in pain processing.
Martin LJ, Smith SB, Khoutorsky A, Magnussen CA, Samoshkin A, Sorge RE, Cho C, Yosefpour N, Sivaselvachandran S, Tohyama S, Cole T, Khuong TM, Mir E, Gibson DG, Wieskopf JS, Sotocinal SG, Austin JS, Meloto CB, Gitt JH, Gkogkas C, Sonenberg N, Greenspan JD, Fillingim RB, Ohrbach R, Slade GD, Knott C, Dubner R, Nackley AG, Ribeiro-da-Silva A, Neely GG, Maixner W, Zaykin DV, Mogil JS, Diatchenko L. Martin LJ, et al. J Clin Invest. 2017 Sep 1;127(9):3353-3366. doi: 10.1172/JCI87406. Epub 2017 Aug 7. J Clin Invest. 2017. PMID: 28783046 Free PMC article.
Male-Specific Conditioned Pain Hypersensitivity in Mice and Humans.
Martin LJ, Acland EL, Cho C, Gandhi W, Chen D, Corley E, Kadoura B, Levy T, Mirali S, Tohyama S, Khan S, MacIntyre LC, Carlson EN, Schweinhardt P, Mogil JS. Martin LJ, et al. Curr Biol. 2019 Jan 21;29(2):192-201.e4. doi: 10.1016/j.cub.2018.11.030. Epub 2019 Jan 10. Curr Biol. 2019. PMID: 30639112 Free article.
917 results