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Conformational dynamics promotes disordered regions from function-dispensable to essential in evolved site-specific DNA recombinases.
Guillén-Pingarrón C, Guillem-Gloria PM, Soni A, Ruiz-Gómez G, Augsburg M, Buchholz F, Anselmi M, Pisabarro MT. Guillén-Pingarrón C, et al. Among authors: augsburg m. Comput Struct Biotechnol J. 2022 Jan 22;20:989-1001. doi: 10.1016/j.csbj.2022.01.010. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35242289 Free PMC article.
Activation of recombinases at specific DNA loci by zinc-finger domain insertions.
Mukhametzyanova L, Schmitt LT, Torres-Rivera J, Rojo-Romanos T, Lansing F, Paszkowski-Rogacz M, Hollak H, Brux M, Augsburg M, Schneider PM, Buchholz F. Mukhametzyanova L, et al. Among authors: augsburg m. Nat Biotechnol. 2024 Jan 31. doi: 10.1038/s41587-023-02121-y. Online ahead of print. Nat Biotechnol. 2024. PMID: 38297187
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM. Hutchins JR, et al. Among authors: augsburg m. Science. 2010 Apr 30;328(5978):593-9. doi: 10.1126/science.1181348. Epub 2010 Apr 1. Science. 2010. PMID: 20360068 Free PMC article.
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.
Poser I, Sarov M, Hutchins JR, Hériché JK, Toyoda Y, Pozniakovsky A, Weigl D, Nitzsche A, Hegemann B, Bird AW, Pelletier L, Kittler R, Hua S, Naumann R, Augsburg M, Sykora MM, Hofemeister H, Zhang Y, Nasmyth K, White KP, Dietzel S, Mechtler K, Durbin R, Stewart AF, Peters JM, Buchholz F, Hyman AA. Poser I, et al. Among authors: augsburg m. Nat Methods. 2008 May;5(5):409-15. doi: 10.1038/nmeth.1199. Epub 2008 Apr 6. Nat Methods. 2008. PMID: 18391959 Free PMC article.