Martina Tholen[Author] - Search Results

Year	Number of Results
2014	1
2015	1
2016	1
2017	2
2018	2
2020	6
2021	1
2022	1
2023	1
2024	0

1

Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis.

Neuwirt E, Magnani G, Ćiković T, Wöhrle S, Fischer L, Kostina A, Flemming S, Fischenich NJ, Saller BS, Gorka O, Renner S, Agarinis C, Parker CN, Boettcher A, Farady CJ, Kesselring R, Berlin C, Backofen R, Rodriguez-Franco M, Kreutz C, Prinz M, Tholen M, Reinheckel T, Ott T, Groß CJ, Jost PJ, Groß O. Neuwirt E, et al. Among authors: tholen m. Sci Signal. 2023 Jan 17;16(768):eabh1083. doi: 10.1126/scisignal.abh1083. Epub 2023 Jan 17. Sci Signal. 2023. PMID: 36649377

2

AND-gate contrast agents for enhanced fluorescence-guided surgery.

Widen JC, Tholen M, Yim JJ, Antaris A, Casey KM, Rogalla S, Klaassen A, Sorger J, Bogyo M. Widen JC, et al. Among authors: tholen m. Nat Biomed Eng. 2021 Mar;5(3):264-277. doi: 10.1038/s41551-020-00616-6. Epub 2020 Sep 28. Nat Biomed Eng. 2021. PMID: 32989286 Free PMC article.

3

Low-level lysosomal membrane permeabilization for limited release and sublethal functions of cathepsin proteases in the cytosol and nucleus.

Reinheckel T, Tholen M. Reinheckel T, et al. Among authors: tholen m. FEBS Open Bio. 2022 Apr;12(4):694-707. doi: 10.1002/2211-5463.13385. Epub 2022 Mar 9. FEBS Open Bio. 2022. PMID: 35203107 Free PMC article. Review.

4

Short-Wave Infrared Fluorescence Chemical Sensor for Detection of Otitis Media.

Yim JJ, Singh SP, Xia A, Kashfi-Sadabad R, Tholen M, Huland DM, Zarabanda D, Cao Z, Solis-Pazmino P, Bogyo M, Valdez TA. Yim JJ, et al. Among authors: tholen m. ACS Sens. 2020 Nov 25;5(11):3411-3419. doi: 10.1021/acssensors.0c01272. Epub 2020 Nov 11. ACS Sens. 2020. PMID: 33175516

5

Optimization of a Protease Activated Probe for Optical Surgical Navigation.

Yim JJ, Tholen M, Klaassen A, Sorger J, Bogyo M. Yim JJ, et al. Among authors: tholen m. Mol Pharm. 2018 Mar 5;15(3):750-758. doi: 10.1021/acs.molpharmaceut.7b00822. Epub 2017 Dec 14. Mol Pharm. 2018. PMID: 29172524

6

Design of Optical-Imaging Probes by Screening of Diverse Substrate Libraries Directly in Disease-Tissue Extracts.

Tholen M, Yim JJ, Groborz K, Yoo E, Martin BA, van den Berg NS, Drag M, Bogyo M. Tholen M, et al. Angew Chem Int Ed Engl. 2020 Oct 19;59(43):19143-19152. doi: 10.1002/anie.202006719. Epub 2020 Aug 26. Angew Chem Int Ed Engl. 2020. PMID: 32589815 Free PMC article.

7

The glucosyltransferase activity of C. difficile Toxin B is required for disease pathogenesis.

Bilverstone TW, Garland M, Cave RJ, Kelly ML, Tholen M, Bouley DM, Kaye P, Minton NP, Bogyo M, Kuehne SA, Melnyk RA. Bilverstone TW, et al. Among authors: tholen m. PLoS Pathog. 2020 Sep 22;16(9):e1008852. doi: 10.1371/journal.ppat.1008852. eCollection 2020 Sep. PLoS Pathog. 2020. PMID: 32960931 Free PMC article.

8

Methods for analysis of near-infrared (NIR) quenched-fluorescent contrast agents in mouse models of cancer.

Widen JC, Tholen M, Yim JJ, Bogyo M. Widen JC, et al. Among authors: tholen m. Methods Enzymol. 2020;639:141-166. doi: 10.1016/bs.mie.2020.04.012. Epub 2020 Apr 29. Methods Enzymol. 2020. PMID: 32475399

9

Chemical Tools for Selective Activity Profiling of Endogenously Expressed MMP-14 in Multicellular Models.

Amara N, Tholen M, Bogyo M. Amara N, et al. Among authors: tholen m. ACS Chem Biol. 2018 Sep 21;13(9):2645-2654. doi: 10.1021/acschembio.8b00562. Epub 2018 Sep 11. ACS Chem Biol. 2018. PMID: 30160940 Free PMC article.

10

The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI.

Garland M, Hryckowian AJ, Tholen M, Bender KO, Van Treuren WW, Loscher S, Sonnenburg JL, Bogyo M. Garland M, et al. Among authors: tholen m. Cell Rep Med. 2020 Apr 21;1(1):100005. doi: 10.1016/j.xcrm.2020.100005. Cell Rep Med. 2020. PMID: 32483557 Free PMC article.

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