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Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, Brauner B, Louie G, Kueider-Paisley A, Suhre K, Saykin AJ, Ekroos K, Meikle PJ, Hood L, Price ND; Alzheimer’s Disease Metabolomics Consortium; Doraiswamy PM, Funk CC, Hernández AI, Kastenmüller G, Baillie R, Han X, Kaddurah-Daouk R. Baloni P, et al. Commun Biol. 2022 Oct 8;5(1):1074. doi: 10.1038/s42003-022-04011-6. Commun Biol. 2022. PMID: 36209301 Free PMC article.
Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine.
Heinken A, Hertel J, Acharya G, Ravcheev DA, Nyga M, Okpala OE, Hogan M, Magnúsdóttir S, Martinelli F, Nap B, Preciat G, Edirisinghe JN, Henry CS, Fleming RMT, Thiele I. Heinken A, et al. Among authors: martinelli f. Nat Biotechnol. 2023 Sep;41(9):1320-1331. doi: 10.1038/s41587-022-01628-0. Epub 2023 Jan 19. Nat Biotechnol. 2023. PMID: 36658342 Free PMC article.
Whole-body modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer's disease.
Martinelli F, Heinken A, Henning AK, Wörheide MA, Hensen T, González A, Arnold M, Asthana S, Budde K, Engelman CD, Estaki M, Grabe HJ, Heston M, Johnson S, Kastenmüller G, Martino C, McDonald D, Rey F, Kilimann I, Peters O, Wang X, Spruth EJ, Schneider A, Fliessbach K, Wiltfang J, Hansen N, Glanz W, Buerger K, Janowitz D, Laske C, Munk MH, Spottke A, Roy N, Nauck M, Teipel S, Knight R, Kaddurah-Daouk R, Bendlin BB, Hertel J, Thiele I. Martinelli F, et al. Res Sq [Preprint]. 2023 Sep 6:rs.3.rs-3306891. doi: 10.21203/rs.3.rs-3306891/v1. Res Sq. 2023. PMID: 37720019 Free PMC article. Updated. Preprint.
APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple continents, age groups, and body sites.
Heinken A, Hulshof TO, Nap B, Martinelli F, Basile A, O'Brolchain A, O'Sullivan NF, Gallagher C, Magee E, McDonagh F, Lalor I, Bergin M, Evans P, Daly R, Farrell R, Delaney RM, Hill S, McAuliffe SR, Kilgannon T, Fleming RMT, Thinnes CC, Thiele I. Heinken A, et al. Among authors: martinelli f. bioRxiv [Preprint]. 2023 Oct 3:2023.10.02.560573. doi: 10.1101/2023.10.02.560573. bioRxiv. 2023. PMID: 37873072 Free PMC article. Preprint.
Whole-body metabolic modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer's disease.
Martinelli F, Heinken A, Henning AK, Ulmer MA, Hensen T, González A, Arnold M, Asthana S, Budde K, Engelman CD, Estaki M, Grabe HJ, Heston MB, Johnson S, Kastenmüller G, Martino C, McDonald D, Rey FE, Kilimann I, Peters O, Wang X, Spruth EJ, Schneider A, Fliessbach K, Wiltfang J, Hansen N, Glanz W, Buerger K, Janowitz D, Laske C, Munk MH, Spottke A, Roy N, Nauck M, Teipel S, Knight R, Kaddurah-Daouk RF, Bendlin BB, Hertel J, Thiele I. Martinelli F, et al. Sci Rep. 2024 Mar 13;14(1):6095. doi: 10.1038/s41598-024-55960-3. Sci Rep. 2024. PMID: 38480804 Free PMC article.
Are biomarkers expression and clinical-pathological factors predictive markers of the efficacy of neoadjuvant chemotherapy for locally advanced cervical cancer?
Ditto A, Longo M, Chiarello G, Mariani L, Paolini B, Leone Roberti Maggiore U, Martinelli F, Bogani G, Raspagliesi F. Ditto A, et al. Among authors: martinelli f. Eur J Surg Oncol. 2024 Mar 25;50(6):108311. doi: 10.1016/j.ejso.2024.108311. Online ahead of print. Eur J Surg Oncol. 2024. PMID: 38554552
391 results