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Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation.
Aoki Y, Han Q, Tome Y, Yamamoto J, Kubota Y, Masaki N, Obara K, Hamada K, Wang JD, Inubushi S, Bouvet M, Clarke SG, Nishida K, Hoffman RM. Aoki Y, et al. Among authors: masaki n. Front Oncol. 2022 Nov 3;12:1009548. doi: 10.3389/fonc.2022.1009548. eCollection 2022. Front Oncol. 2022. PMID: 36408173 Free PMC article.
Over-methylation of Histone H3 Lysines Is a Common Molecular Change Among the Three Major Types of Soft-tissue Sarcoma in Patient-derived Xenograft (PDX) Mouse Models.
Aoki Y, Yamamoto J, Tome Y, Hamada K, Masaki N, Inubushi S, Tashiro Y, Bouvet M, Endo I, Nishida K, Hoffman RM. Aoki Y, et al. Among authors: masaki n. Cancer Genomics Proteomics. 2021 Nov-Dec;18(6):715-721. doi: 10.21873/cgp.20292. Cancer Genomics Proteomics. 2021. PMID: 34697064 Free PMC article.
Histone H3 lysine-trimethylation markers are decreased by recombinant methioninase and increased by methotrexate at concentrations which inhibit methionine-addicted osteosarcoma cell proliferation.
Aoki Y, Tome Y, Han Q, Yamamoto J, Hamada K, Masaki N, Bouvet M, Nishida K, Hoffman RM. Aoki Y, et al. Among authors: masaki n. Biochem Biophys Rep. 2021 Nov 26;28:101177. doi: 10.1016/j.bbrep.2021.101177. eCollection 2021 Dec. Biochem Biophys Rep. 2021. PMID: 34877414 Free PMC article.
The First Mouse Model of Meckel's Diverticulum Carcinoma.
Masaki N, Yonemura Y, Wu NF, Samonte C, Hozumi C, Kubota Y, Aoki Y, Bouvet M, Miyazaki J, Hoffman RM. Masaki N, et al. In Vivo. 2022 Jul-Aug;36(4):1603-1607. doi: 10.21873/invivo.12870. In Vivo. 2022. PMID: 35738609 Free PMC article.
441 results