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Discovery of Gemilukast (ONO-6950), a Dual CysLT1 and CysLT2 Antagonist As a Therapeutic Agent for Asthma.
Itadani S, Yashiro K, Aratani Y, Sekiguchi T, Kinoshita A, Moriguchi H, Ohta N, Takahashi S, Ishida A, Tajima Y, Hisaichi K, Ima M, Ueda J, Egashira H, Sekioka T, Kadode M, Yonetomi Y, Nakao T, Inoue A, Nomura H, Kitamine T, Fujita M, Nabe T, Yamaura Y, Matsumura N, Imagawa A, Nakayama Y, Takeuchi J, Ohmoto K. Itadani S, et al. Among authors: matsumura n. J Med Chem. 2015 Aug 13;58(15):6093-113. doi: 10.1021/acs.jmedchem.5b00741. Epub 2015 Jul 22. J Med Chem. 2015. PMID: 26200813
A new CysLT1 and CysLT2 receptors-mediated anaphylaxis guinea pig model.
Sekioka T, Kadode M, Osakada N, Fujita M, Matsumura N, Yamaura Y, Nakade S, Nabe T, Kawabata K. Sekioka T, et al. Among authors: matsumura n. Prostaglandins Leukot Essent Fatty Acids. 2017 Apr;119:18-24. doi: 10.1016/j.plefa.2017.03.002. Epub 2017 Mar 8. Prostaglandins Leukot Essent Fatty Acids. 2017. PMID: 28410666
ONO-8430506: A Novel Autotaxin Inhibitor That Enhances the Antitumor Effect of Paclitaxel in a Breast Cancer Model.
Iwaki Y, Ohhata A, Nakatani S, Hisaichi K, Okabe Y, Hiramatsu A, Watanabe T, Yamamoto S, Nishiyama T, Kobayashi J, Hirooka Y, Moriguchi H, Maeda T, Katoh M, Komichi Y, Ota H, Matsumura N, Okada M, Sugiyama T, Saga H, Imagawa A. Iwaki Y, et al. Among authors: matsumura n. ACS Med Chem Lett. 2020 May 14;11(6):1335-1341. doi: 10.1021/acsmedchemlett.0c00200. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32551021 Free PMC article.
Pyrrolo[1,2-b]pyridazines, pyrrolo[2,1-f]triazin-4(3H)-ones, and related compounds as novel corticotropin-releasing factor 1 (CRF₁) receptor antagonists.
Saito T, Obitsu T, Kohno H, Sugimoto I, Matsushita T, Nishiyama T, Hirota T, Takeda H, Matsumura N, Ueno S, Kishi A, Kagamiishi Y, Nakai H, Takaoka Y. Saito T, et al. Among authors: matsumura n. Bioorg Med Chem. 2012 Jan 15;20(2):1122-38. doi: 10.1016/j.bmc.2011.11.015. Epub 2011 Dec 3. Bioorg Med Chem. 2012. PMID: 22196514
Prediction Accuracy of Mechanism-Based Oral Absorption Model for Dogs.
Akiyama Y, Kimoto T, Mukumoto H, Miyake S, Ito S, Taniguchi T, Nomura Y, Matsumura N, Fujita T, Sugano K. Akiyama Y, et al. Among authors: matsumura n. J Pharm Sci. 2019 Aug;108(8):2728-2736. doi: 10.1016/j.xphs.2019.03.015. Epub 2019 Mar 21. J Pharm Sci. 2019. PMID: 30905705
759 results