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2019 2
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2022 2
2023 2
2024 0

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The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine.
Yu D, Richardson NE, Green CL, Spicer AB, Murphy ME, Flores V, Jang C, Kasza I, Nikodemova M, Wakai MH, Tomasiewicz JL, Yang SE, Miller BR, Pak HH, Brinkman JA, Rojas JM, Quinn WJ 3rd, Cheng EP, Konon EN, Haider LR, Finke M, Sonsalla M, Alexander CM, Rabinowitz JD, Baur JA, Malecki KC, Lamming DW. Yu D, et al. Among authors: wakai mh. Cell Metab. 2021 May 4;33(5):905-922.e6. doi: 10.1016/j.cmet.2021.03.025. Epub 2021 Apr 21. Cell Metab. 2021. PMID: 33887198 Free PMC article.
The Activin/FLRG Pathway Associates with Poor COVID-19 Outcomes in Hospitalized Patients.
McAleavy M, Zhang Q, Ehmann PJ, Xu J, Wipperman MF, Ajithdoss D, Pan L, Wakai M, Simonson R, Gadi A, Oyejide A, Hamon SC, Boyapati A, Morton LG, Shavlakadze T, Kyratsous CA, Glass DJ. McAleavy M, et al. Among authors: wakai m. Mol Cell Biol. 2022 Jan 20;42(1):e0046721. doi: 10.1128/MCB.00467-21. Epub 2021 Nov 1. Mol Cell Biol. 2022. PMID: 34723652 Free PMC article. Clinical Trial.
Regulation of metabolic health by dietary histidine in mice.
Flores V, Spicer AB, Sonsalla MM, Richardson NE, Yu D, Sheridan GE, Trautman ME, Babygirija R, Cheng EP, Rojas JM, Yang SE, Wakai MH, Hubbell R, Kasza I, Tomasiewicz JL, Green CL, Dantoin C, Alexander CM, Baur JA, Malecki KC, Lamming DW. Flores V, et al. Among authors: wakai mh. J Physiol. 2023 Jun;601(11):2139-2163. doi: 10.1113/JP283261. Epub 2022 Sep 27. J Physiol. 2023. PMID: 36086823
Hypothalamic mTORC2 is essential for metabolic health and longevity.
Chellappa K, Brinkman JA, Mukherjee S, Morrison M, Alotaibi MI, Carbajal KA, Alhadeff AL, Perron IJ, Yao R, Purdy CS, DeFelice DM, Wakai MH, Tomasiewicz J, Lin A, Meyer E, Peng Y, Arriola Apelo SI, Puglielli L, Betley JN, Paschos GK, Baur JA, Lamming DW. Chellappa K, et al. Among authors: wakai mh. Aging Cell. 2019 Oct;18(5):e13014. doi: 10.1111/acel.13014. Epub 2019 Aug 1. Aging Cell. 2019. PMID: 31373126 Free PMC article.