Maynard AT - Search Results

1

Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor.

Wang LH, Yang XY, Zhang X, Mihalic K, Fan YX, Xiao W, Howard OM, Appella E, Maynard AT, Farrar WL. Wang LH, et al. Among authors: maynard at. Nat Med. 2004 Jan;10(1):40-7. doi: 10.1038/nm969. Epub 2003 Dec 14. Nat Med. 2004. PMID: 14702633

2

Synthesis and biological properties of novel pyridinioalkanoyl thiolesters (PATE) as anti-HIV-1 agents that target the viral nucleocapsid protein zinc fingers.

Turpin JA, Song Y, Inman JK, Huang M, Wallqvist A, Maynard A, Covell DG, Rice WG, Appella E. Turpin JA, et al. J Med Chem. 1999 Jan 14;42(1):67-86. doi: 10.1021/jm9802517. J Med Chem. 1999. PMID: 9888834

3

Naturally occurring CCR5 extracellular and transmembrane domain variants affect HIV-1 Co-receptor and ligand binding function.

Howard OM, Shirakawa AK, Turpin JA, Maynard A, Tobin GJ, Carrington M, Oppenheim JJ, Dean M. Howard OM, et al. J Biol Chem. 1999 Jun 4;274(23):16228-34. doi: 10.1074/jbc.274.23.16228. J Biol Chem. 1999. PMID: 10347178 Free article.

4

Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins.

Huang M, Maynard A, Turpin JA, Graham L, Janini GM, Covell DG, Rice WG. Huang M, et al. J Med Chem. 1998 Apr 23;41(9):1371-81. doi: 10.1021/jm9708543. J Med Chem. 1998. PMID: 9554870

5

Comparison of the specificity of interaction of cellular and viral zinc-binding domains with 2-mercaptobenzamide thioesters.

Jenkins LM, Durell SR, Maynard AT, Stahl SJ, Inman JK, Appella E, Legault P, Omichinski JG. Jenkins LM, et al. Among authors: maynard at. J Am Chem Soc. 2006 Sep 13;128(36):11964-76. doi: 10.1021/ja063329e. J Am Chem Soc. 2006. PMID: 16953638

6

Reactivity of zinc finger cores: analysis of protein packing and electrostatic screening.

Maynard AT, Covell DG. Maynard AT, et al. J Am Chem Soc. 2001 Feb 14;123(6):1047-58. doi: 10.1021/ja0011616. J Am Chem Soc. 2001. PMID: 11456658

7

Reactivity of the HIV-1 nucleocapsid protein p7 zinc finger domains from the perspective of density-functional theory.

Maynard AT, Huang M, Rice WG, Covell DG. Maynard AT, et al. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11578-83. doi: 10.1073/pnas.95.20.11578. Proc Natl Acad Sci U S A. 1998. PMID: 9751708 Free PMC article.

8

Design and synthesis of spirocyclic compounds as HCV replication inhibitors by targeting viral NS4B protein.

Tai VW, Garrido D, Price DJ, Maynard A, Pouliot JJ, Xiong Z, Seal JW 3rd, Creech KL, Kryn LH, Baughman TM, Peat AJ. Tai VW, et al. Bioorg Med Chem Lett. 2014 May 15;24(10):2288-94. doi: 10.1016/j.bmcl.2014.03.080. Epub 2014 Apr 3. Bioorg Med Chem Lett. 2014. PMID: 24731273

9

Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymerase.

Maynard A, Crosby RM, Ellis B, Hamatake R, Hong Z, Johns BA, Kahler KM, Koble C, Leivers A, Leivers MR, Mathis A, Peat AJ, Pouliot JJ, Roberts CD, Samano V, Schmidt RM, Smith GK, Spaltenstein A, Stewart EL, Thommes P, Turner EM, Voitenleitner C, Walker JT, Waitt G, Weatherhead J, Weaver K, Williams S, Wright L, Xiong ZZ, Haigh D, Shotwell JB. Maynard A, et al. J Med Chem. 2014 Mar 13;57(5):1902-13. doi: 10.1021/jm400317w. Epub 2013 May 29. J Med Chem. 2014. PMID: 23672667

10

Statistical tools for virtual screening.

Krumrine JR, Maynard AT, Lerman CL. Krumrine JR, et al. Among authors: maynard at. J Med Chem. 2005 Nov 17;48(23):7477-81. doi: 10.1021/jm0501026. J Med Chem. 2005. PMID: 16279807

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