McComb S - Search Results

1

TNFR2 is required for RIP1-dependent cell death in human leukemia.

Aguadé-Gorgorió J, McComb S, Eckert C, Guinot A, Marovca B, Mezzatesta C, Jenni S, Abduli L, Schrappe M, Dobay MP, Stanulla M, von Stackelberg A, Cario G, Bourquin JP, Bornhauser BC. Aguadé-Gorgorió J, et al. Among authors: mccomb s. Blood Adv. 2020 Oct 13;4(19):4823-4833. doi: 10.1182/bloodadvances.2019000796. Blood Adv. 2020. PMID: 33027529 Free PMC article.

2

Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL.

McComb S, Aguadé-Gorgorió J, Harder L, Marovca B, Cario G, Eckert C, Schrappe M, Stanulla M, von Stackelberg A, Bourquin JP, Bornhauser BC. McComb S, et al. Sci Transl Med. 2016 May 18;8(339):339ra70. doi: 10.1126/scitranslmed.aad2986. Sci Transl Med. 2016. PMID: 27194728

3

Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7.

McComb S, Chan PK, Guinot A, Hartmannsdottir H, Jenni S, Dobay MP, Bourquin JP, Bornhauser BC. McComb S, et al. Sci Adv. 2019 Jul 31;5(7):eaau9433. doi: 10.1126/sciadv.aau9433. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31392262 Free PMC article.

4

Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9.

Behrmann L, McComb S, Aguadé-Gorgorió J, Huang Y, Hermann M, Pelczar P, Aguzzi A, Bourquin JP, Bornhauser BC. Behrmann L, et al. Among authors: mccomb s. Bio Protoc. 2017 Apr 5;7(7):e2222. doi: 10.21769/BioProtoc.2222. eCollection 2017 Apr 5. Bio Protoc. 2017. PMID: 34541223 Free PMC article.

5

Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages.

McComb S, Cessford E, Alturki NA, Joseph J, Shutinoski B, Startek JB, Gamero AM, Mossman KL, Sad S. McComb S, et al. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):E3206-13. doi: 10.1073/pnas.1407068111. Epub 2014 Jul 21. Proc Natl Acad Sci U S A. 2014. PMID: 25049377 Free PMC article.

6

cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation.

McComb S, Cheung HH, Korneluk RG, Wang S, Krishnan L, Sad S. McComb S, et al. Cell Death Differ. 2012 Nov;19(11):1791-801. doi: 10.1038/cdd.2012.59. Epub 2012 May 11. Cell Death Differ. 2012. PMID: 22576661 Free PMC article.

7

Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis.

Alturki NA, McComb S, Ariana A, Rijal D, Korneluk RG, Sun SC, Alnemri E, Sad S. Alturki NA, et al. Among authors: mccomb s. Cell Death Dis. 2018 May 22;9(6):592. doi: 10.1038/s41419-018-0672-0. Cell Death Dis. 2018. PMID: 29789521 Free PMC article.

8

IRAK4 is essential for TLR9-induced suppression of Epstein-Barr virus BZLF1 transcription in Akata Burkitt's lymphoma cells.

Jordi M, Marty J, Mordasini V, Lünemann A, McComb S, Bernasconi M, Nadal D. Jordi M, et al. Among authors: mccomb s. PLoS One. 2017 Oct 31;12(10):e0186614. doi: 10.1371/journal.pone.0186614. eCollection 2017. PLoS One. 2017. PMID: 29088270 Free PMC article.

9

Differentiated macrophages acquire a pro-inflammatory and cell death-resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1.

Rijal D, Ariana A, Wight A, Kim K, Alturki NA, Aamir Z, Ametepe ES, Korneluk RG, Tiedje C, Menon MB, Gaestel M, McComb S, Sad S. Rijal D, et al. Among authors: mccomb s. J Biol Chem. 2018 Jul 27;293(30):11913-11927. doi: 10.1074/jbc.RA118.003614. Epub 2018 Jun 13. J Biol Chem. 2018. PMID: 29899110 Free PMC article.

10

MAP4K4 controlled integrin β1 activation and c-Met endocytosis are associated with invasive behavior of medulloblastoma cells.

Tripolitsioti D, Kumar KS, Neve A, Migliavacca J, Capdeville C, Rushing EJ, Ma M, Kijima N, Sharma A, Pruschy M, McComb S, Taylor MD, Grotzer MA, Baumgartner M. Tripolitsioti D, et al. Among authors: mccomb s. Oncotarget. 2018 May 1;9(33):23220-23236. doi: 10.18632/oncotarget.25294. eCollection 2018 May 1. Oncotarget. 2018. PMID: 29796184 Free PMC article.

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