McCormick F - Search Results

1

Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex.

Kwon JJ, Hajian B, Bian Y, Young LC, Amor AJ, Fuller JR, Fraley CV, Sykes AM, So J, Pan J, Baker L, Lee SJ, Wheeler DB, Mayhew DL, Persky NS, Yang X, Root DE, Barsotti AM, Stamford AW, Perry CK, Burgin A, McCormick F, Lemke CT, Hahn WC, Aguirre AJ. Kwon JJ, et al. Among authors: mccormick f. Nature. 2022 Sep;609(7926):408-415. doi: 10.1038/s41586-022-04928-2. Epub 2022 Jul 13. Nature. 2022. PMID: 35831509 Free PMC article.

2

The GTPase superfamily: conserved structure and molecular mechanism.

Bourne HR, Sanders DA, McCormick F. Bourne HR, et al. Among authors: mccormick f. Nature. 1991 Jan 10;349(6305):117-27. doi: 10.1038/349117a0. Nature. 1991. PMID: 1898771 Review.

3

The GTPase superfamily: a conserved switch for diverse cell functions.

Bourne HR, Sanders DA, McCormick F. Bourne HR, et al. Among authors: mccormick f. Nature. 1990 Nov 8;348(6297):125-32. doi: 10.1038/348125a0. Nature. 1990. PMID: 2122258 Review.

4

Suppression of c-ras transformation by GTPase-activating protein.

Zhang K, DeClue JE, Vass WC, Papageorge AG, McCormick F, Lowy DR. Zhang K, et al. Among authors: mccormick f. Nature. 1990 Aug 23;346(6286):754-6. doi: 10.1038/346754a0. Nature. 1990. PMID: 2201922

5

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells.

Tetsu O, McCormick F. Tetsu O, et al. Among authors: mccormick f. Nature. 1999 Apr 1;398(6726):422-6. doi: 10.1038/18884. Nature. 1999. PMID: 10201372

6

A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity.

Rodriguez-Viciana P, Oses-Prieto J, Burlingame A, Fried M, McCormick F. Rodriguez-Viciana P, et al. Among authors: mccormick f. Mol Cell. 2006 Apr 21;22(2):217-30. doi: 10.1016/j.molcel.2006.03.027. Mol Cell. 2006. PMID: 16630891 Free article.

7

Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond.

Holderfield M, Deuker MM, McCormick F, McMahon M. Holderfield M, et al. Among authors: mccormick f. Nat Rev Cancer. 2014 Jul;14(7):455-67. doi: 10.1038/nrc3760. Nat Rev Cancer. 2014. PMID: 24957944 Free PMC article. Review.

8

SHOC2-MRAS-PP1 complex positively regulates RAF activity and contributes to Noonan syndrome pathogenesis.

Young LC, Hartig N, Boned Del Río I, Sari S, Ringham-Terry B, Wainwright JR, Jones GG, McCormick F, Rodriguez-Viciana P. Young LC, et al. Among authors: mccormick f. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10576-E10585. doi: 10.1073/pnas.1720352115. Epub 2018 Oct 22. Proc Natl Acad Sci U S A. 2018. PMID: 30348783 Free PMC article.

9

KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation.

Tran TH, Chan AH, Young LC, Bindu L, Neale C, Messing S, Dharmaiah S, Taylor T, Denson JP, Esposito D, Nissley DV, Stephen AG, McCormick F, Simanshu DK. Tran TH, et al. Among authors: mccormick f. Nat Commun. 2021 Feb 19;12(1):1176. doi: 10.1038/s41467-021-21422-x. Nat Commun. 2021. PMID: 33608534 Free PMC article.

10

The Metabolic Landscape of RAS-Driven Cancers from biology to therapy.

Mukhopadhyay S, Vander Heiden MG, McCormick F. Mukhopadhyay S, et al. Among authors: mccormick f. Nat Cancer. 2021 Mar;2(3):271-283. doi: 10.1038/s43018-021-00184-x. Epub 2021 Mar 24. Nat Cancer. 2021. PMID: 33870211 Free PMC article. Review.

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