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Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss.
Refaey ME, McGee-Lawrence ME, Fulzele S, Kennedy EJ, Bollag WB, Elsalanty M, Zhong Q, Ding KH, Bendzunas NG, Shi XM, Xu J, Hill WD, Johnson MH, Hunter M, Pierce JL, Yu K, Hamrick MW, Isales CM. Refaey ME, et al. J Bone Miner Res. 2017 Nov;32(11):2182-2193. doi: 10.1002/jbmr.3224. Epub 2017 Aug 14. J Bone Miner Res. 2017. PMID: 28727234 Free PMC article.
Deletion of protein kinase D1 in osteoprogenitor cells results in decreased osteogenesis in vitro and reduced bone mineral density in vivo.
Bollag WB, Choudhary V, Zhong Q, Ding KH, Xu J, Elsayed R, Yu K, Su Y, Bailey LJ, Shi XM, Elsalanty M, Johnson MH, McGee-Lawrence ME, Isales CM. Bollag WB, et al. Mol Cell Endocrinol. 2018 Feb 5;461:22-31. doi: 10.1016/j.mce.2017.08.005. Epub 2017 Aug 12. Mol Cell Endocrinol. 2018. PMID: 28811183 Free PMC article.
Amino acids as signaling molecules modulating bone turnover.
Ding KH, Cain M, Davis M, Bergson C, McGee-Lawrence M, Perkins C, Hardigan T, Shi X, Zhong Q, Xu J, Bollag WB, Hill W, Elsalanty M, Hunter M, Isales MC, Lopez P, Hamrick M, Isales CM. Ding KH, et al. Bone. 2018 Oct;115:15-24. doi: 10.1016/j.bone.2018.02.028. Epub 2018 Feb 27. Bone. 2018. PMID: 29499416 Free PMC article. Review.
Monomethylfumarate protects against ovariectomy-related changes in body composition.
Bollag AE, Guo T, Ding KH, Choudhary V, Chen X, Zhong Q, Xu J, Yu K, Awad ME, Elsalanty M, Johnson MH, McGee-Lawrence ME, Bollag WB, Isales CM. Bollag AE, et al. J Endocrinol. 2019 Jul 1:JOE-18-0691.R3. doi: 10.1530/JOE-18-0691. Online ahead of print. J Endocrinol. 2019. PMID: 31362266 Free PMC article.
The glucocorticoid receptor in osteoprogenitors regulates bone mass and marrow fat.
Pierce JL, Ding KH, Xu J, Sharma AK, Yu K, Del Mazo Arbona N, Rodriguez-Santos Z, Bernard P, Bollag WB, Johnson MH, Hamrick MW, Begun DL, Shi XM, Isales CM, McGee-Lawrence ME. Pierce JL, et al. J Endocrinol. 2019 Jul 1:JOE-19-0230.R1. doi: 10.1530/JOE-19-0230. Online ahead of print. J Endocrinol. 2019. PMID: 31370004 Free PMC article.
Age-related increase of kynurenine enhances miR29b-1-5p to decrease both CXCL12 signaling and the epigenetic enzyme Hdac3 in bone marrow stromal cells.
Elmansi AM, Hussein KA, Herrero SM, Periyasamy-Thandavan S, Aguilar-Pérez A, Kondrikova G, Kondrikov D, Eisa NH, Pierce JL, Kaiser H, Ding KH, Walker AL, Jiang X, Bollag WB, Elsalanty M, Zhong Q, Shi XM, Su Y, Johnson M, Hunter M, Reitman C, Volkman BF, Hamrick MW, Isales CM, Fulzele S, McGee-Lawrence ME, Hill WD. Elmansi AM, et al. Bone Rep. 2020 Apr 23;12:100270. doi: 10.1016/j.bonr.2020.100270. eCollection 2020 Jun. Bone Rep. 2020. PMID: 32395570 Free PMC article.
94 results