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Mitochondrial pyruvate carriers are required for myocardial stress adaptation.
Zhang Y, Taufalele PV, Cochran JD, Robillard-Frayne I, Marx JM, Soto J, Rauckhorst AJ, Tayyari F, Pewa AD, Gray LR, Teesch LM, Puchalska P, Funari TR, McGlauflin R, Zimmerman K, Kutschke WJ, Cassier T, Hitchcock S, Lin K, Kato KM, Stueve JL, Haff L, Weiss RM, Cox JE, Rutter J, Taylor EB, Crawford PA, Lewandowski ED, Des Rosiers C, Abel ED. Zhang Y, et al. Among authors: mcglauflin r. Nat Metab. 2020 Nov;2(11):1248-1264. doi: 10.1038/s42255-020-00288-1. Epub 2020 Oct 26. Nat Metab. 2020. PMID: 33106689 Free PMC article.
Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission.
Tsushima K, Bugger H, Wende AR, Soto J, Jenson GA, Tor AR, McGlauflin R, Kenny HC, Zhang Y, Souvenir R, Hu XX, Sloan CL, Pereira RO, Lira VA, Spitzer KW, Sharp TL, Shoghi KI, Sparagna GC, Rog-Zielinska EA, Kohl P, Khalimonchuk O, Schaffer JE, Abel ED. Tsushima K, et al. Among authors: mcglauflin r. Circ Res. 2018 Jan 5;122(1):58-73. doi: 10.1161/CIRCRESAHA.117.311307. Epub 2017 Nov 1. Circ Res. 2018. PMID: 29092894 Free PMC article.
Publisher Correction: Mitochondrial pyruvate carriers are required for myocardial stress adaptation.
Zhang Y, Taufalele PV, Cochran JD, Robillard-Frayne I, Marx JM, Soto J, Rauckhorst AJ, Tayyari F, Pewa AD, Gray LR, Teesch LM, Puchalska P, Funari TR, McGlauflin R, Zimmerman K, Kutschke WJ, Cassier T, Hitchcock S, Lin K, Kato KM, Stueve JL, Haff L, Weiss RM, Cox JE, Rutter J, Taylor EB, Crawford PA, Lewandowski ED, Des Rosiers C, Abel ED. Zhang Y, et al. Among authors: mcglauflin r. Nat Metab. 2020 Dec;2(12):1498. doi: 10.1038/s42255-020-00322-2. Nat Metab. 2020. PMID: 33208925 No abstract available.
OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance.
Pereira RO, Tadinada SM, Zasadny FM, Oliveira KJ, Pires KMP, Olvera A, Jeffers J, Souvenir R, Mcglauflin R, Seei A, Funari T, Sesaki H, Potthoff MJ, Adams CM, Anderson EJ, Abel ED. Pereira RO, et al. Among authors: mcglauflin r. EMBO J. 2017 Jul 14;36(14):2126-2145. doi: 10.15252/embj.201696179. Epub 2017 Jun 12. EMBO J. 2017. PMID: 28607005 Free PMC article.