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Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis.
Sveidahl Johansen O, Ma T, Hansen JB, Markussen LK, Schreiber R, Reverte-Salisa L, Dong H, Christensen DP, Sun W, Gnad T, Karavaeva I, Nielsen TS, Kooijman S, Cero C, Dmytriyeva O, Shen Y, Razzoli M, O'Brien SL, Kuipers EN, Nielsen CH, Orchard W, Willemsen N, Jespersen NZ, Lundh M, Sustarsic EG, Hallgren CM, Frost M, McGonigle S, Isidor MS, Broholm C, Pedersen O, Hansen JB, Grarup N, Hansen T, Kjær A, Granneman JG, Babu MM, Calebiro D, Nielsen S, Rydén M, Soccio R, Rensen PCN, Treebak JT, Schwartz TW, Emanuelli B, Bartolomucci A, Pfeifer A, Zechner R, Scheele C, Mandrup S, Gerhart-Hines Z. Sveidahl Johansen O, et al. Among authors: mcgonigle s. Cell. 2021 Jun 24;184(13):3502-3518.e33. doi: 10.1016/j.cell.2021.04.037. Epub 2021 May 27. Cell. 2021. PMID: 34048700 Free PMC article.
Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis.
Sahu BS, Razzoli M, McGonigle S, Pallais JP, Nguyen ME, Sadahiro M, Jiang C, Lin WJ, Kelley KA, Rodriguez P, Mansk R, Cero C, Caviola G, Palanza P, Rao L, Beetch M, Alejandro E, Sham YY, Frontini A, Salton SR, Bartolomucci A. Sahu BS, et al. Among authors: mcgonigle s. Mol Metab. 2023 Oct;76:101781. doi: 10.1016/j.molmet.2023.101781. Epub 2023 Jul 21. Mol Metab. 2023. PMID: 37482186 Free PMC article.
Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis.
Sahu BS, Razzoli M, McGonigle S, Pallais JP, Nguyen ME, Sadahiro M, Jiang C, Lin WJ, Kelley KA, Rodriguez P, Mansk R, Cero C, Caviola G, Palanza P, Rao L, Beetch M, Alejandro E, Sham YY, Frontini A, Salton SR, Bartolomucci A. Sahu BS, et al. Among authors: mcgonigle s. bioRxiv [Preprint]. 2023 Mar 24:2023.03.23.532619. doi: 10.1101/2023.03.23.532619. bioRxiv. 2023. PMID: 36993202 Free PMC article. Updated. Preprint.
Clinical potential of microdystrophin as a surrogate endpoint.
Boehler JF, Brown KJ, Beatka M, Gonzalez JP, Donisa Dreghici R, Soustek-Kramer M, McGonigle S, Ganot A, Palmer T, Lowie C, Chamberlain JS, Lawlor MW, Morris CA. Boehler JF, et al. Among authors: mcgonigle s. Neuromuscul Disord. 2023 Jan;33(1):40-49. doi: 10.1016/j.nmd.2022.12.007. Epub 2022 Dec 14. Neuromuscul Disord. 2023. PMID: 36575103 Free article. Review.
First-in-human study of the PARP/tankyrase inhibitor E7449 in patients with advanced solid tumours and evaluation of a novel drug-response predictor.
Plummer R, Dua D, Cresti N, Drew Y, Stephens P, Foegh M, Knudsen S, Sachdev P, Mistry BM, Dixit V, McGonigle S, Hall N, Matijevic M, McGrath S, Sarker D. Plummer R, et al. Among authors: mcgonigle s. Br J Cancer. 2020 Aug;123(4):525-533. doi: 10.1038/s41416-020-0916-5. Epub 2020 Jun 11. Br J Cancer. 2020. PMID: 32523090 Free PMC article. Clinical Trial.
Neuropilin-1 drives tumor-specific uptake of chlorotoxin.
McGonigle S, Majumder U, Kolber-Simonds D, Wu J, Hart A, Noland T, TenDyke K, Custar D, Li D, Du H, Postema MHD, Lai WG, Twine NC, Woodall-Jappe M, Nomoto K. McGonigle S, et al. Cell Commun Signal. 2019 Jun 17;17(1):67. doi: 10.1186/s12964-019-0368-9. Cell Commun Signal. 2019. PMID: 31208428 Free PMC article.
36 results