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Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts.
Peters MC, McGrath KW, Hawkins GA, Hastie AT, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Holguin F, Wenzel SE, Woodruff PG, Bleecker ER, Fahy JV; National Heart, Lung, and Blood Institute Severe Asthma Research Program. Peters MC, et al. Among authors: mcgrath kw. Lancet Respir Med. 2016 Jul;4(7):574-584. doi: 10.1016/S2213-2600(16)30048-0. Epub 2016 Jun 6. Lancet Respir Med. 2016. PMID: 27283230 Free PMC article.
A large subgroup of mild-to-moderate asthma is persistently noneosinophilic.
McGrath KW, Icitovic N, Boushey HA, Lazarus SC, Sutherland ER, Chinchilli VM, Fahy JV; Asthma Clinical Research Network of the National Heart, Lung, and Blood Institute. McGrath KW, et al. Am J Respir Crit Care Med. 2012 Mar 15;185(6):612-9. doi: 10.1164/rccm.201109-1640OC. Epub 2012 Jan 20. Am J Respir Crit Care Med. 2012. PMID: 22268133 Free PMC article. Clinical Trial.
The H antigen at epithelial surfaces is associated with susceptibility to asthma exacerbation.
Innes AL, McGrath KW, Dougherty RH, McCulloch CE, Woodruff PG, Seibold MA, Okamoto KS, Ingmundson KJ, Solon MC, Carrington SD, Fahy JV. Innes AL, et al. Among authors: mcgrath kw. Am J Respir Crit Care Med. 2011 Jan 15;183(2):189-94. doi: 10.1164/rccm.201003-0488OC. Epub 2010 Aug 23. Am J Respir Crit Care Med. 2011. PMID: 20732988 Free PMC article.