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Selectively targeting myeloid-derived suppressor cells through TRAIL receptor 2 to enhance the efficacy of CAR T cell therapy for treatment of breast cancer.
Nalawade SA, Shafer P, Bajgain P, McKenna MK, Ali A, Kelly L, Joubert J, Gottschalk S, Watanabe N, Leen A, Parihar R, Vera Valdes JF, Hoyos V. Nalawade SA, et al. Among authors: mckenna mk. J Immunother Cancer. 2021 Nov;9(11):e003237. doi: 10.1136/jitc-2021-003237. J Immunother Cancer. 2021. PMID: 34815355 Free PMC article.
Engineered off-the-shelf therapeutic T cells resist host immune rejection.
Mo F, Watanabe N, McKenna MK, Hicks MJ, Srinivasan M, Gomes-Silva D, Atilla E, Smith T, Ataca Atilla P, Ma R, Quach D, Heslop HE, Brenner MK, Mamonkin M. Mo F, et al. Among authors: mckenna mk. Nat Biotechnol. 2021 Jan;39(1):56-63. doi: 10.1038/s41587-020-0601-5. Epub 2020 Jul 13. Nat Biotechnol. 2021. PMID: 32661440 Free PMC article.
Modulating TNFα activity allows transgenic IL15-Expressing CLL-1 CAR T cells to safely eliminate acute myeloid leukemia.
Ataca Atilla P, McKenna MK, Tashiro H, Srinivasan M, Mo F, Watanabe N, Simons BW, McLean Stevens A, Redell MS, Heslop HE, Mamonkin M, Brenner MK, Atilla E. Ataca Atilla P, et al. Among authors: mckenna mk. J Immunother Cancer. 2020 Sep;8(2):e001229. doi: 10.1136/jitc-2020-001229. J Immunother Cancer. 2020. PMID: 32938629 Free PMC article.
Clinical CAR-T Cell and Oncolytic Virotherapy for Cancer Treatment.
Watanabe N, McKenna MK, Rosewell Shaw A, Suzuki M. Watanabe N, et al. Among authors: mckenna mk. Mol Ther. 2021 Feb 3;29(2):505-520. doi: 10.1016/j.ymthe.2020.10.023. Epub 2020 Oct 31. Mol Ther. 2021. PMID: 33130314 Free PMC article. Review.
Generation of CAR T-cells using γ-retroviral vector.
Watanabe N, McKenna MK. Watanabe N, et al. Among authors: mckenna mk. Methods Cell Biol. 2022;167:171-183. doi: 10.1016/bs.mcb.2021.06.014. Epub 2021 Jul 30. Methods Cell Biol. 2022. PMID: 35152995 Free PMC article.
33 results