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Page 1
Microscopic mechanism of DNA damage searching by hOGG1.
Nucleic Acids Res. 2014 Aug;42(14):9295-303. doi: 10.1093/nar/gku621. Epub 2014 Jul 12.
Nucleic Acids Res. 2014.
PMID: 25016526
Free PMC article.
Unique Hydrogen Bonding of Adenine with the Oxidatively Damaged Base 8-Oxoguanine Enables Specific Recognition and Repair by DNA Glycosylase MutY.
Majumdar C, McKibbin PL, Krajewski AE, Manlove AH, Lee JK, David SS.
Majumdar C, et al. Among authors: mckibbin pl.
J Am Chem Soc. 2020 Dec 2;142(48):20340-20350. doi: 10.1021/jacs.0c06767. Epub 2020 Nov 17.
J Am Chem Soc. 2020.
PMID: 33202125
Free PMC article.
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The DNA repair enzyme MUTYH potentiates cytotoxicity of the alkylating agent MNNG by interacting with abasic sites.
Raetz AG, Banda DM, Ma X, Xu G, Rajavel AN, McKibbin PL, Lebrilla CB, David SS.
Raetz AG, et al. Among authors: mckibbin pl.
J Biol Chem. 2020 Mar 13;295(11):3692-3707. doi: 10.1074/jbc.RA119.010497. Epub 2020 Jan 30.
J Biol Chem. 2020.
PMID: 32001618
Free PMC article.
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Structure-Activity Relationships Reveal Key Features of 8-Oxoguanine: A Mismatch Detection by the MutY Glycosylase.
Manlove AH, McKibbin PL, Doyle EL, Majumdar C, Hamm ML, David SS.
Manlove AH, et al. Among authors: mckibbin pl.
ACS Chem Biol. 2017 Sep 15;12(9):2335-2344. doi: 10.1021/acschembio.7b00389. Epub 2017 Aug 8.
ACS Chem Biol. 2017.
PMID: 28723094
Free PMC article.
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Surprising repair activities of nonpolar analogs of 8-oxoG expose features of recognition and catalysis by base excision repair glycosylases.
McKibbin PL, Kobori A, Taniguchi Y, Kool ET, David SS.
McKibbin PL, et al.
J Am Chem Soc. 2012 Jan 25;134(3):1653-61. doi: 10.1021/ja208510m. Epub 2012 Jan 9.
J Am Chem Soc. 2012.
PMID: 22175854
Free PMC article.
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Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair.
McKibbin PL, Fleming AM, Towheed MA, Van Houten B, Burrows CJ, David SS.
McKibbin PL, et al.
J Am Chem Soc. 2013 Sep 18;135(37):13851-61. doi: 10.1021/ja4059469. Epub 2013 Sep 5.
J Am Chem Soc. 2013.
PMID: 23930966
Free PMC article.
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