McKnight AT - Search Results

1

PD 176252--the first high affinity non-peptide gastrin-releasing peptide (BB2) receptor antagonist.

Ashwood V, Brownhill V, Higginbottom M, Horwell DC, Hughes J, Lewthwaite RA, McKnight AT, Pinnock RD, Pritchard MC, Suman-Chauhan N, Webb C, Williams SC. Ashwood V, et al. Among authors: mcknight at. Bioorg Med Chem Lett. 1998 Sep 22;8(18):2589-94. doi: 10.1016/s0960-894x(98)00462-4. Bioorg Med Chem Lett. 1998. PMID: 9873586

2

Rational design of high affinity tachykinin NK2 receptor antagonists.

Boyle S, Guard S, Hodgson J, Horwell DC, Howson W, Hughes J, McKnight A, Martin K, Pritchard MC, Watling KJ, et al. Boyle S, et al. Bioorg Med Chem. 1994 Feb;2(2):101-13. doi: 10.1016/s0968-0896(00)82006-4. Bioorg Med Chem. 1994. PMID: 7922121

3

Rational design of high affinity tachykinin NK1 receptor antagonists.

Boyle S, Guard S, Higginbottom M, Horwell DC, Howson W, McKnight AT, Martin K, Pritchard MC, O'Toole J, Raphy J, et al. Boyle S, et al. Among authors: mcknight at. Bioorg Med Chem. 1994 May;2(5):357-70. doi: 10.1016/s0968-0896(00)82192-6. Bioorg Med Chem. 1994. PMID: 7922147

4

Use of a dipeptide chemical library in the development of non-peptide tachykinin NK3 receptor selective antagonists.

Boden P, Eden JM, Hodgson J, Horwell DC, Hughes J, McKnight AT, Lewthwaite RA, Pritchard MC, Raphy J, Meecham K, Ratcliffe GS, Suman-Chauhan N, Woodruff GN. Boden P, et al. Among authors: mcknight at. J Med Chem. 1996 Apr 12;39(8):1664-75. doi: 10.1021/jm950892r. J Med Chem. 1996. PMID: 8648606

5

Activation of the cloned human NK3 receptor in Chinese Hamster Ovary cells characterized by the cellular acidification response using the Cytosensor microphysiometer.

Jordan RE, Smart D, Grimson P, Suman-Chauhan N, McKnight AT. Jordan RE, et al. Among authors: mcknight at. Br J Pharmacol. 1998 Oct;125(4):761-6. doi: 10.1038/sj.bjp.0702156. Br J Pharmacol. 1998. PMID: 9831912 Free PMC article.

6

The effect of CCKB/gastrin antagonists on stimulated gastric acid secretion in the anaesthetized rat.

Hayward NJ, Harding M, Lloyd SA, McKnight AT, Hughes J, Woodruff GN. Hayward NJ, et al. Among authors: mcknight at. Br J Pharmacol. 1991 Dec;104(4):973-7. doi: 10.1111/j.1476-5381.1991.tb12535.x. Br J Pharmacol. 1991. PMID: 1687371 Free PMC article.

7

Peptoid CCK receptor antagonists: pharmacological evaluation of CCKA, CCKB and mixed CCKA/B receptor antagonists.

Singh L, Field MJ, Hill DR, Horwell DC, McKnight AT, Roberts E, Tang KW, Woodruff GN. Singh L, et al. Among authors: mcknight at. Eur J Pharmacol. 1995 Nov 14;286(2):185-91. doi: 10.1016/0014-2999(95)00445-q. Eur J Pharmacol. 1995. PMID: 8605955

8

Gabapentin inhibits the substance P-facilitated K(+)-evoked release of [(3)H]glutamate from rat caudial trigeminal nucleus slices.

Maneuf YP, Hughes J, McKnight AT. Maneuf YP, et al. Among authors: mcknight at. Pain. 2001 Aug;93(2):191-196. doi: 10.1016/S0304-3959(01)00316-5. Pain. 2001. PMID: 11427331

9

Evidence that cholecystokinin induces immediate early gene expression in the brainstem, hypothalamus and amygdala of the rat by a CCKA receptor mechanism.

Day HE, McKnight AT, Poat JA, Hughes J. Day HE, et al. Among authors: mcknight at. Neuropharmacology. 1994 Jun;33(6):719-27. doi: 10.1016/0028-3908(94)90111-2. Neuropharmacology. 1994. PMID: 7936109

10

Effect of gastrin-releasing peptide on rat hippocampal extracellular GABA levels and seizures in the audiogenic seizure-prone DBA/2 mouse.

Andrews N, Davis B, Gonzalez MI, Oles R, Singh L, McKnight AT. Andrews N, et al. Among authors: mcknight at. Brain Res. 2000 Mar 24;859(2):386-9. doi: 10.1016/s0006-8993(00)02010-2. Brain Res. 2000. PMID: 10719092

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