McMahon RM - Search Results

1

Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis.

McMahon RM, Friis L, Siebold C, Friese MA, Fugger L, Jones EY. McMahon RM, et al. Acta Crystallogr D Biol Crystallogr. 2011 May;67(Pt 5):447-54. doi: 10.1107/S0907444911007888. Epub 2011 Apr 13. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 21543847 Free PMC article.

2

Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis.

Friese MA, Jakobsen KB, Friis L, Etzensperger R, Craner MJ, McMahon RM, Jensen LT, Huygelen V, Jones EY, Bell JI, Fugger L. Friese MA, et al. Among authors: mcmahon rm. Nat Med. 2008 Nov;14(11):1227-35. doi: 10.1038/nm.1881. Epub 2008 Oct 26. Nat Med. 2008. PMID: 18953350

3

T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides.

Harkiolaki M, Holmes SL, Svendsen P, Gregersen JW, Jensen LT, McMahon R, Friese MA, van Boxel G, Etzensperger R, Tzartos JS, Kranc K, Sainsbury S, Harlos K, Mellins ED, Palace J, Esiri MM, van der Merwe PA, Jones EY, Fugger L. Harkiolaki M, et al. Immunity. 2009 Mar 20;30(3):348-57. doi: 10.1016/j.immuni.2009.01.009. Immunity. 2009. PMID: 19303388 Free article.

4

Dissection of the multiple sclerosis associated DR2 haplotype.

Etzensperger R, McMahon RM, Jones EY, Fugger L. Etzensperger R, et al. Among authors: mcmahon rm. J Autoimmun. 2008 Nov;31(3):201-7. doi: 10.1016/j.jaut.2008.04.016. Epub 2008 Jun 2. J Autoimmun. 2008. PMID: 18513924 Review.

5

An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1 gene.

Ramagopalan SV, McMahon R, Dyment DA, Sadovnick AD, Ebers GC, Wittkowski KM. Ramagopalan SV, et al. BMC Med Genet. 2009 Feb 4;10:10. doi: 10.1186/1471-2350-10-10. BMC Med Genet. 2009. PMID: 19193207 Free PMC article.

6

Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility.

McMahon RM, Coinçon M, Tay S, Heras B, Morton CJ, Scanlon MJ, Martin JL. McMahon RM, et al. Acta Crystallogr D Biol Crystallogr. 2015 Dec 1;71(Pt 12):2386-95. doi: 10.1107/S1399004715018519. Epub 2015 Nov 26. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26627647 Free PMC article.

7

Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1.

Mohanty B, Rimmer K, McMahon RM, Headey SJ, Vazirani M, Shouldice SR, Coinçon M, Tay S, Morton CJ, Simpson JS, Martin JL, Scanlon MJ. Mohanty B, et al. Among authors: mcmahon rm. PLoS One. 2017 Mar 27;12(3):e0173436. doi: 10.1371/journal.pone.0173436. eCollection 2017. PLoS One. 2017. PMID: 28346540 Free PMC article.

8

Four structural subclasses of the antivirulence drug target disulfide oxidoreductase DsbA provide a platform for design of subclass-specific inhibitors.

McMahon RM, Premkumar L, Martin JL. McMahon RM, et al. Biochim Biophys Acta. 2014 Aug;1844(8):1391-401. doi: 10.1016/j.bbapap.2014.01.013. Epub 2014 Jan 30. Biochim Biophys Acta. 2014. PMID: 24487020 Review.

9

Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA.

Duprez W, Bachu P, Stoermer MJ, Tay S, McMahon RM, Fairlie DP, Martin JL. Duprez W, et al. Among authors: mcmahon rm. PLoS One. 2015 Jul 30;10(7):e0133805. doi: 10.1371/journal.pone.0133805. eCollection 2015. PLoS One. 2015. PMID: 26225423 Free PMC article.

10

Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase.

Christensen S, Grøftehauge MK, Byriel K, Huston WM, Furlong E, Heras B, Martin JL, McMahon RM. Christensen S, et al. Among authors: mcmahon rm. PLoS One. 2016 Dec 28;11(12):e0168485. doi: 10.1371/journal.pone.0168485. eCollection 2016. PLoS One. 2016. PMID: 28030602 Free PMC article.

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