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IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer.
Mace TA, Shakya R, Pitarresi JR, Swanson B, McQuinn CW, Loftus S, Nordquist E, Cruz-Monserrate Z, Yu L, Young G, Zhong X, Zimmers TA, Ostrowski MC, Ludwig T, Bloomston M, Bekaii-Saab T, Lesinski GB. Mace TA, et al. Among authors: mcquinn cw. Gut. 2018 Feb;67(2):320-332. doi: 10.1136/gutjnl-2016-311585. Epub 2016 Oct 21. Gut. 2018. PMID: 27797936 Free PMC article.
Exploratory analysis of immune checkpoint receptor expression by circulating T cells and tumor specimens in patients receiving neo-adjuvant chemotherapy for operable breast cancer.
Wesolowski R, Stiff A, Quiroga D, McQuinn C, Li Z, Nitta H, Savardekar H, Benner B, Ramaswamy B, Lustberg M, Layman RM, Macrae E, Kassem M, Williams N, Sardesai S, VanDeusen J, Stover D, Cherian M, Mace TA, Yu L, Duggan M, Carson WE 3rd. Wesolowski R, et al. BMC Cancer. 2020 May 19;20(1):445. doi: 10.1186/s12885-020-06949-4. BMC Cancer. 2020. PMID: 32429929 Free PMC article.
A multi-center, single-arm, phase Ib study of pembrolizumab (MK-3475) in combination with chemotherapy for patients with advanced colorectal cancer: HCRN GI14-186.
Herting CJ, Farren MR, Tong Y, Liu Z, O'Neil B, Bekaii-Saab T, Noonan A, McQuinn C, Mace TA, Shaib W, Wu C, El-Rayes BF, Shahda S, Lesinski GB. Herting CJ, et al. Cancer Immunol Immunother. 2021 Nov;70(11):3337-3348. doi: 10.1007/s00262-021-02986-5. Epub 2021 Jun 23. Cancer Immunol Immunother. 2021. PMID: 34160684 Free PMC article. Clinical Trial.
Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell- and CXCR3-dependent manner.
Ware MB, Phillips M, McQuinn C, Zaidi MY, Knochelmann HM, Greene E, Robinson B, Herting CJ, Mace TA, Chen Z, Zhang C, Farren MR, Ruggieri AN, Bowers JS, Shakya R, Farris AB, Young G, Carson WE 3rd, El-Rayes B, Paulos CM, Lesinski GB. Ware MB, et al. JCI Insight. 2023 Apr 24;8(8):e155006. doi: 10.1172/jci.insight.155006. JCI Insight. 2023. PMID: 36881480 Free PMC article.