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Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation.
Putnam AL, Safinia N, Medvec A, Laszkowska M, Wray M, Mintz MA, Trotta E, Szot GL, Liu W, Lares A, Lee K, Laing A, Lechler RI, Riley JL, Bluestone JA, Lombardi G, Tang Q. Putnam AL, et al. Among authors: medvec a. Am J Transplant. 2013 Nov;13(11):3010-20. doi: 10.1111/ajt.12433. Epub 2013 Sep 18. Am J Transplant. 2013. PMID: 24102808 Free PMC article.
TCR affinity and specificity requirements for human regulatory T-cell function.
Plesa G, Zheng L, Medvec A, Wilson CB, Robles-Oteiza C, Liddy N, Bennett AD, Gavarret J, Vuidepot A, Zhao Y, Blazar BR, Jakobsen BK, Riley JL. Plesa G, et al. Among authors: medvec a. Blood. 2012 Apr 12;119(15):3420-30. doi: 10.1182/blood-2011-09-377051. Epub 2012 Feb 7. Blood. 2012. PMID: 22318202 Free PMC article.
Strength of PD-1 signaling differentially affects T-cell effector functions.
Wei F, Zhong S, Ma Z, Kong H, Medvec A, Ahmed R, Freeman GJ, Krogsgaard M, Riley JL. Wei F, et al. Among authors: medvec a. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2480-9. doi: 10.1073/pnas.1305394110. Epub 2013 Apr 22. Proc Natl Acad Sci U S A. 2013. PMID: 23610399 Free PMC article.
Differential Reliance on Lipid Metabolism as a Salvage Pathway Underlies Functional Differences of T Cell Subsets in Poor Nutrient Environments.
Ecker C, Guo L, Voicu S, Gil-de-Gómez L, Medvec A, Cortina L, Pajda J, Andolina M, Torres-Castillo M, Donato JL, Mansour S, Zynda ER, Lin PY, Varela-Rohena A, Blair IA, Riley JL. Ecker C, et al. Among authors: medvec a. Cell Rep. 2018 Apr 17;23(3):741-755. doi: 10.1016/j.celrep.2018.03.084. Cell Rep. 2018. PMID: 29669281 Free PMC article.