MitoStores: a place for precursors to ride out the storm

EMBO J. 2023 Apr 3;42(7):e113576. doi: 10.15252/embj.2023113576. Epub 2023 Mar 6.

Abstract

The fate of unimported mitochondrial precursors has been increasingly studied in recent years, mostly focusing on protein degradation. In this issue of the EMBO journal, Krämer et al discovered MitoStores, a new protective mechanism that temporarily stores mitochondrial proteins in cytosolic deposits.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Mitochondria* / metabolism
  • Mitochondrial Proteins* / metabolism

Substances

  • Mitochondrial Proteins

Grants and funding