Megson IL - Search Results

1

Evaluation of the antioxidant properties of N-acetylcysteine in human platelets: prerequisite for bioconversion to glutathione for antioxidant and antiplatelet activity.

Gibson KR, Neilson IL, Barrett F, Winterburn TJ, Sharma S, MacRury SM, Megson IL. Gibson KR, et al. Among authors: megson il. J Cardiovasc Pharmacol. 2009 Oct;54(4):319-26. doi: 10.1097/FJC.0b013e3181b6e77b. J Cardiovasc Pharmacol. 2009. PMID: 19668088

2

2-arachidonyl glycerol activates platelets via conversion to arachidonic acid and not by direct activation of cannabinoid receptors.

Keown OP, Winterburn TJ, Wainwright CL, Macrury SM, Neilson I, Barrett F, Leslie SJ, Megson IL. Keown OP, et al. Among authors: megson il. Br J Clin Pharmacol. 2010 Aug;70(2):180-8. doi: 10.1111/j.1365-2125.2010.03697.x. Br J Clin Pharmacol. 2010. PMID: 20653671 Free PMC article.

3

Therapeutic potential of N-acetylcysteine as an antiplatelet agent in patients with type-2 diabetes.

Gibson KR, Winterburn TJ, Barrett F, Sharma S, MacRury SM, Megson IL. Gibson KR, et al. Among authors: megson il. Cardiovasc Diabetol. 2011 May 21;10:43. doi: 10.1186/1475-2840-10-43. Cardiovasc Diabetol. 2011. PMID: 21600014 Free PMC article.

4

N-Acetylcysteine inhibits platelet-monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial.

Treweeke AT, Winterburn TJ, Mackenzie I, Barrett F, Barr C, Rushworth GF, Dransfield I, MacRury SM, Megson IL. Treweeke AT, et al. Among authors: megson il. Diabetologia. 2012 Nov;55(11):2920-8. doi: 10.1007/s00125-012-2685-z. Epub 2012 Aug 31. Diabetologia. 2012. PMID: 22935960 Free PMC article. Clinical Trial.

5

Endothelial cell oxidative stress in diabetes: a key driver of cardiovascular complications?

Shaw A, Doherty MK, Mutch NJ, MacRury SM, Megson IL. Shaw A, et al. Among authors: megson il. Biochem Soc Trans. 2014 Aug;42(4):928-33. doi: 10.1042/BST20140113. Biochem Soc Trans. 2014. PMID: 25109981 Review.

6

Continuous subcutaneous insulin infusion in patients with type 2 diabetes: a cohort study to establish the relationship between glucose control and plasma oxidized low density lipoprotein.

Megson IL, Treweeke AT, Shaw A, MacRury SM, Setford S, Frias JP, Anhalt H. Megson IL, et al. J Diabetes Sci Technol. 2015 May;9(3):573-80. doi: 10.1177/1932296815570359. Epub 2015 Feb 3. J Diabetes Sci Technol. 2015. PMID: 25652563 Free PMC article.

7

Why Is COVID-19 More Severe in Patients With Diabetes? The Role of Angiotensin-Converting Enzyme 2, Endothelial Dysfunction and the Immunoinflammatory System.

Roberts J, Pritchard AL, Treweeke AT, Rossi AG, Brace N, Cahill P, MacRury SM, Wei J, Megson IL. Roberts J, et al. Among authors: megson il. Front Cardiovasc Med. 2021 Feb 3;7:629933. doi: 10.3389/fcvm.2020.629933. eCollection 2020. Front Cardiovasc Med. 2021. PMID: 33614744 Free PMC article. Review.

8

Diabetic fatty liver disease is associated with specific changes in blood-borne markers.

Sharma S, Barrett F, Adamson J, Todd A, Megson IL, Zentler-Munro PL, MacRury SM. Sharma S, et al. Among authors: megson il. Diabetes Metab Res Rev. 2012 May;28(4):343-8. doi: 10.1002/dmrr.2269. Diabetes Metab Res Rev. 2012. PMID: 22576780

9

Existing and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits.

Rushworth GF, Megson IL. Rushworth GF, et al. Among authors: megson il. Pharmacol Ther. 2014 Feb;141(2):150-9. doi: 10.1016/j.pharmthera.2013.09.006. Epub 2013 Sep 28. Pharmacol Ther. 2014. PMID: 24080471 Review.

10

Vascular effects of apelin in vivo in man.

Japp AG, Cruden NL, Amer DA, Li VK, Goudie EB, Johnston NR, Sharma S, Neilson I, Webb DJ, Megson IL, Flapan AD, Newby DE. Japp AG, et al. Among authors: megson il. J Am Coll Cardiol. 2008 Sep 9;52(11):908-13. doi: 10.1016/j.jacc.2008.06.013. J Am Coll Cardiol. 2008. PMID: 18772060 Free article.

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