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Mechanism of allosteric activation of SAMHD1 by dGTP.
Ji X, Wu Y, Yan J, Mehrens J, Yang H, DeLucia M, Hao C, Gronenborn AM, Skowronski J, Ahn J, Xiong Y. Ji X, et al. Among authors: mehrens j. Nat Struct Mol Biol. 2013 Nov;20(11):1304-9. doi: 10.1038/nsmb.2692. Epub 2013 Oct 20. Nat Struct Mol Biol. 2013. PMID: 24141705 Free PMC article.
Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.
Wu Y, Koharudin LMI, Mehrens J, DeLucia M, Byeon CH, Byeon IL, Calero G, Ahn J, Gronenborn AM. Wu Y, et al. Among authors: mehrens j. J Biol Chem. 2015 Jul 17;290(29):17935-17945. doi: 10.1074/jbc.M115.665513. Epub 2015 Jun 4. J Biol Chem. 2015. PMID: 26045556 Free PMC article.
Neuropilin-1 mediates neutrophil elastase uptake and cross-presentation in breast cancer cells.
Kerros C, Tripathi SC, Zha D, Mehrens JM, Sergeeva A, Philips AV, Qiao N, Peters HL, Katayama H, Sukhumalchandra P, Ruisaard KE, Perakis AA, St John LS, Lu S, Mittendorf EA, Clise-Dwyer K, Herrmann AC, Alatrash G, Toniatti C, Hanash SM, Ma Q, Molldrem JJ. Kerros C, et al. Among authors: mehrens jm. J Biol Chem. 2017 Jun 16;292(24):10295-10305. doi: 10.1074/jbc.M116.773051. Epub 2017 May 3. J Biol Chem. 2017. PMID: 28468826 Free PMC article.
A Novel T-Cell Engaging Bi-specific Antibody Targeting the Leukemia Antigen PR1/HLA-A2.
Herrmann AC, Im JS, Pareek S, Ruiz-Vasquez W, Lu S, Sergeeva A, Mehrens J, He H, Alatrash G, Sukhumalchandra P, St John L, Clise-Dwyer K, Zha D, Molldrem JJ. Herrmann AC, et al. Among authors: mehrens j. Front Immunol. 2019 Jan 18;9:3153. doi: 10.3389/fimmu.2018.03153. eCollection 2018. Front Immunol. 2019. PMID: 30713535 Free PMC article.