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TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth.
Chan TY, Egbert CM, Maxson JE, Siddiqui A, Larsen LJ, Kohler K, Balasooriya ER, Pennington KL, Tsang TM, Frey M, Soderblom EJ, Geng H, Müschen M, Forostyan TV, Free S, Mercenne G, Banks CJ, Valdoz J, Whatcott CJ, Foulks JM, Bearss DJ, O'Hare T, Huang DCS, Christensen KA, Moody J, Warner SL, Tyner JW, Andersen JL. Chan TY, et al. Among authors: mercenne g. Nat Commun. 2021 Sep 9;12(1):5337. doi: 10.1038/s41467-021-25622-3. Nat Commun. 2021. PMID: 34504101 Free PMC article.
Global landscape of HIV-human protein complexes.
Jäger S, Cimermancic P, Gulbahce N, Johnson JR, McGovern KE, Clarke SC, Shales M, Mercenne G, Pache L, Li K, Hernandez H, Jang GM, Roth SL, Akiva E, Marlett J, Stephens M, D'Orso I, Fernandes J, Fahey M, Mahon C, O'Donoghue AJ, Todorovic A, Morris JH, Maltby DA, Alber T, Cagney G, Bushman FD, Young JA, Chanda SK, Sundquist WI, Kortemme T, Hernandez RD, Craik CS, Burlingame A, Sali A, Frankel AD, Krogan NJ. Jäger S, et al. Among authors: mercenne g. Nature. 2011 Dec 21;481(7381):365-70. doi: 10.1038/nature10719. Nature. 2011. PMID: 22190034 Free PMC article.
Angiomotin functions in HIV-1 assembly and budding.
Mercenne G, Alam SL, Arii J, Lalonde MS, Sundquist WI. Mercenne G, et al. Elife. 2015 Jan 29;4:e03778. doi: 10.7554/eLife.03778. Elife. 2015. PMID: 25633977 Free PMC article.
RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis.
Rheinemann L, Downhour DM, Bredbenner K, Mercenne G, Davenport KA, Schmitt PT, Necessary CR, McCullough J, Schmitt AP, Simon SM, Sundquist WI, Elde NC. Rheinemann L, et al. Among authors: mercenne g. Cell. 2021 Oct 14;184(21):5419-5431.e16. doi: 10.1016/j.cell.2021.09.008. Epub 2021 Sep 30. Cell. 2021. PMID: 34597582 Free PMC article.
A Drosophila screen identifies NKCC1 as a modifier of NGLY1 deficiency.
Talsness DM, Owings KG, Coelho E, Mercenne G, Pleinis JM, Partha R, Hope KA, Zuberi AR, Clark NL, Lutz CM, Rodan AR, Chow CY. Talsness DM, et al. Among authors: mercenne g. Elife. 2020 Dec 14;9:e57831. doi: 10.7554/eLife.57831. Elife. 2020. PMID: 33315011 Free PMC article.
12 results