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Page 1
B-cell tumor development in Tet2-deficient mice.
Mouly E, Ghamlouch H, Della-Valle V, Scourzic L, Quivoron C, Roos-Weil D, Pawlikowska P, Saada V, Diop MK, Lopez CK, Fontenay M, Dessen P, Touw IP, Mercher T, Aoufouchi S, Bernard OA. Mouly E, et al. Among authors: mercher t. Blood Adv. 2018 Mar 27;2(6):703-714. doi: 10.1182/bloodadvances.2017014118. Blood Adv. 2018. PMID: 29581109 Free PMC article.
A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.
Bernard OA, Busson-LeConiat M, Ballerini P, Mauchauffé M, Della Valle V, Monni R, Nguyen Khac F, Mercher T, Penard-Lacronique V, Pasturaud P, Gressin L, Heilig R, Daniel MT, Lessard M, Berger R. Bernard OA, et al. Among authors: mercher t. Leukemia. 2001 Oct;15(10):1495-504. doi: 10.1038/sj.leu.2402249. Leukemia. 2001. PMID: 11587205
JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model.
Mercher T, Wernig G, Moore SA, Levine RL, Gu TL, Fröhling S, Cullen D, Polakiewicz RD, Bernard OA, Boggon TJ, Lee BH, Gilliland DG. Mercher T, et al. Blood. 2006 Oct 15;108(8):2770-9. doi: 10.1182/blood-2006-04-014712. Epub 2006 Jun 27. Blood. 2006. PMID: 16804112 Free PMC article.
Ott1(Rbm15) has pleiotropic roles in hematopoietic development.
Raffel GD, Mercher T, Shigematsu H, Williams IR, Cullen DE, Akashi K, Bernard OA, Gilliland DG. Raffel GD, et al. Among authors: mercher t. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6001-6. doi: 10.1073/pnas.0609041104. Epub 2007 Mar 21. Proc Natl Acad Sci U S A. 2007. PMID: 17376872 Free PMC article.
The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model.
Mercher T, Raffel GD, Moore SA, Cornejo MG, Baudry-Bluteau D, Cagnard N, Jesneck JL, Pikman Y, Cullen D, Williams IR, Akashi K, Shigematsu H, Bourquin JP, Giovannini M, Vainchenker W, Levine RL, Lee BH, Bernard OA, Gilliland DG. Mercher T, et al. J Clin Invest. 2009 Apr;119(4):852-64. doi: 10.1172/JCI35901. Epub 2009 Mar 16. J Clin Invest. 2009. PMID: 19287095 Free PMC article.
Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia.
Chapiro E, Russell L, Lainey E, Kaltenbach S, Ragu C, Della-Valle V, Hanssens K, Macintyre EA, Radford-Weiss I, Delabesse E, Cavé H, Mercher T, Harrison CJ, Nguyen-Khac F, Dubreuil P, Bernard OA. Chapiro E, et al. Among authors: mercher t. Leukemia. 2010 Mar;24(3):642-5. doi: 10.1038/leu.2009.231. Epub 2009 Nov 12. Leukemia. 2010. PMID: 19907440 No abstract available.
Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification.
Cornejo MG, Mabialah V, Sykes SM, Khandan T, Lo Celso C, Lopez CK, Rivera-Muñoz P, Rameau P, Tothova Z, Aster JC, DePinho RA, Scadden DT, Gilliland DG, Mercher T. Cornejo MG, et al. Among authors: mercher t. Blood. 2011 Aug 4;118(5):1264-73. doi: 10.1182/blood-2011-01-328567. Epub 2011 Jun 7. Blood. 2011. PMID: 21653327 Free PMC article.
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis.
Quivoron C, Couronné L, Della Valle V, Lopez CK, Plo I, Wagner-Ballon O, Do Cruzeiro M, Delhommeau F, Arnulf B, Stern MH, Godley L, Opolon P, Tilly H, Solary E, Duffourd Y, Dessen P, Merle-Beral H, Nguyen-Khac F, Fontenay M, Vainchenker W, Bastard C, Mercher T, Bernard OA. Quivoron C, et al. Among authors: mercher t. Cancer Cell. 2011 Jul 12;20(1):25-38. doi: 10.1016/j.ccr.2011.06.003. Epub 2011 Jun 30. Cancer Cell. 2011. PMID: 21723201 Free article.
74 results