Mercola D - Search Results

1

EGR-1, the reluctant suppression factor: EGR-1 is known to function in the regulation of growth, differentiation, and also has significant tumor suppressor activity and a mechanism involving the induction of TGF-beta1 is postulated to account for this suppressor activity.

Liu C, Calogero A, Ragona G, Adamson E, Mercola D. Liu C, et al. Among authors: mercola d. Crit Rev Oncog. 1996;7(1-2):101-25. Crit Rev Oncog. 1996. PMID: 9109500 Review.

2

Egr-1 negatively regulates human tumor cell growth via the DNA-binding domain.

Huang RP, Liu C, Fan Y, Mercola D, Adamson ED. Huang RP, et al. Among authors: mercola d. Cancer Res. 1995 Nov 1;55(21):5054-62. Cancer Res. 1995. PMID: 7585551

3

Transformation-specific pattern of phosphorylation of c-Jun, Jun-B, Jun-D and Egr-1 in v-sis transformed cells.

Grover-Bardwick A, Adamson E, Mercola D. Grover-Bardwick A, et al. Among authors: mercola d. Carcinogenesis. 1994 Aug;15(8):1667-74. doi: 10.1093/carcin/15.8.1667. Carcinogenesis. 1994. PMID: 8055649

The degree of phosphorylation of c-Jun, Jun-B, Jun-D and Egr-1 transcription factors was examined during normal growth and during a prolonged period of defined transformation of NIH-3T3 cells which conditionally express v-sis [Mercola, D. et al. (1992) Oncoge …

The degree of phosphorylation of c-Jun, Jun-B, Jun-D and Egr-1 transcription factors was examined during normal growth and during a p …

4

Transcription factor EGR-1 suppresses the growth and transformation of human HT-1080 fibrosarcoma cells by induction of transforming growth factor beta 1.

Liu C, Adamson E, Mercola D. Liu C, et al. Among authors: mercola d. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11831-6. doi: 10.1073/pnas.93.21.11831. Proc Natl Acad Sci U S A. 1996. PMID: 8876223 Free PMC article.

5

Suppression of growth and transformation and induction of apoptosis by EGR-1.

Liu C, Rangnekar VM, Adamson E, Mercola D. Liu C, et al. Among authors: mercola d. Cancer Gene Ther. 1998 Jan-Feb;5(1):3-28. Cancer Gene Ther. 1998. PMID: 9476963 Review.

6

The transcription factor EGR-1 suppresses transformation of human fibrosarcoma HT1080 cells by coordinated induction of transforming growth factor-beta1, fibronectin, and plasminogen activator inhibitor-1.

Liu C, Yao J, de Belle I, Huang RP, Adamson E, Mercola D. Liu C, et al. Among authors: mercola d. J Biol Chem. 1999 Feb 12;274(7):4400-11. doi: 10.1074/jbc.274.7.4400. J Biol Chem. 1999. PMID: 9933644 Free article.

Re-expression of EGR-1 in fibrosarcoma HT1080 suppresses transformation including tumorigenicity (Huang, R.-P., Liu, C., Fan, Y., Mercola, D., and Adamson, E. (1995) Cancer Res. 55, 5054-5062) owing in part to up-regulation of the transforming growth factor (TGF)-be …

Re-expression of EGR-1 in fibrosarcoma HT1080 suppresses transformation including tumorigenicity (Huang, R.-P., Liu, C., Fan, Y., Mercola …

7

The transcription factor EGR-1 directly transactivates the fibronectin gene and enhances attachment of human glioblastoma cell line U251.

Liu C, Yao J, Mercola D, Adamson E. Liu C, et al. Among authors: mercola d. J Biol Chem. 2000 Jul 7;275(27):20315-23. doi: 10.1074/jbc.M909046199. J Biol Chem. 2000. PMID: 10783396 Free article.

8

The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin.

Baron V, Adamson ED, Calogero A, Ragona G, Mercola D. Baron V, et al. Among authors: mercola d. Cancer Gene Ther. 2006 Feb;13(2):115-24. doi: 10.1038/sj.cgt.7700896. Cancer Gene Ther. 2006. PMID: 16138117 Free PMC article. Review.

9

Egr1 transcription factor: multiple roles in prostate tumor cell growth and survival.

Adamson ED, Mercola D. Adamson ED, et al. Among authors: mercola d. Tumour Biol. 2002 Mar-Apr;23(2):93-102. doi: 10.1159/000059711. Tumour Biol. 2002. PMID: 12065847 Review.

10

Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence.

Krones-Herzig A, Adamson E, Mercola D. Krones-Herzig A, et al. Among authors: mercola d. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3233-8. doi: 10.1073/pnas.2628034100. Epub 2003 Mar 10. Proc Natl Acad Sci U S A. 2003. PMID: 12629205 Free PMC article.

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