Mesecar AD - Search Results

1

Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory activities.

Maiti A, Reddy PV, Sturdy M, Marler L, Pegan SD, Mesecar AD, Pezzuto JM, Cushman M. Maiti A, et al. Among authors: mesecar ad. J Med Chem. 2009 Apr 9;52(7):1873-84. doi: 10.1021/jm801335z. J Med Chem. 2009. PMID: 19265439 Free PMC article.

2

Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer.

Sun B, Hoshino J, Jermihov K, Marler L, Pezzuto JM, Mesecar AD, Cushman M. Sun B, et al. Among authors: mesecar ad. Bioorg Med Chem. 2010 Jul 15;18(14):5352-66. doi: 10.1016/j.bmc.2010.05.042. Epub 2010 May 24. Bioorg Med Chem. 2010. PMID: 20558073 Free PMC article.

3

Potential chemopreventive agents based on the structure of the lead compound 2-bromo-1-hydroxyphenazine, isolated from Streptomyces species, strain CNS284.

Conda-Sheridan M, Marler L, Park EJ, Kondratyuk TP, Jermihov K, Mesecar AD, Pezzuto JM, Asolkar RN, Fenical W, Cushman M. Conda-Sheridan M, et al. Among authors: mesecar ad. J Med Chem. 2010 Dec 23;53(24):8688-99. doi: 10.1021/jm1011066. Epub 2010 Nov 24. J Med Chem. 2010. PMID: 21105712 Free PMC article.

4

Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS.

Choi Y, Jermihov K, Nam SJ, Sturdy M, Maloney K, Qiu X, Chadwick LR, Main M, Chen SN, Mesecar AD, Farnsworth NR, Pauli GF, Fenical W, Pezzuto JM, van Breemen RB. Choi Y, et al. Among authors: mesecar ad. Anal Chem. 2011 Feb 1;83(3):1048-52. doi: 10.1021/ac1028424. Epub 2010 Dec 30. Anal Chem. 2011. PMID: 21192729 Free PMC article.

5

Design, synthesis, and biological evaluation of potent quinoline and pyrroloquinoline ammosamide analogues as inhibitors of quinone reductase 2.

Reddy PV, Jensen KC, Mesecar AD, Fanwick PE, Cushman M. Reddy PV, et al. Among authors: mesecar ad. J Med Chem. 2012 Jan 12;55(1):367-77. doi: 10.1021/jm201251c. Epub 2011 Dec 29. J Med Chem. 2012. PMID: 22206487 Free PMC article.

6

Constituents of Musa x paradisiaca cultivar with the potential to induce the phase II enzyme, quinone reductase.

Jang DS, Park EJ, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Santarsiero BD, Mesecar AD, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Jang DS, et al. Among authors: mesecar ad. J Agric Food Chem. 2002 Oct 23;50(22):6330-4. doi: 10.1021/jf0206670. J Agric Food Chem. 2002. PMID: 12381112

7

Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity.

Su BN, Park EJ, Nikolic D, Santarsiero BD, Mesecar AD, Vigo JS, Graham JG, Cabieses F, van Breemen RB, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Su BN, et al. Among authors: mesecar ad. J Org Chem. 2003 Mar 21;68(6):2350-61. doi: 10.1021/jo020542u. J Org Chem. 2003. PMID: 12636402

8

Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1.

Liu G, Eggler AL, Dietz BM, Mesecar AD, Bolton JL, Pezzuto JM, van Breemen RB. Liu G, et al. Among authors: mesecar ad. Anal Chem. 2005 Oct 1;77(19):6407-14. doi: 10.1021/ac050892r. Anal Chem. 2005. PMID: 16194107

9

Miliusanes, a class of cytotoxic agents from Miliusa sinensis.

Zhang HJ, Ma C, Nguyen VH, Nguyen MC, Tan GT, Santarsiero BD, Mesecar AD, Soejarto DD, Pezzuto JM, Fong HH. Zhang HJ, et al. Among authors: mesecar ad. J Med Chem. 2006 Jan 26;49(2):693-708. doi: 10.1021/jm0509492. J Med Chem. 2006. PMID: 16420055

10

Design and synthesis of 2-pyridones as novel inhibitors of the Bacillus anthracis enoyl-ACP reductase.

Tipparaju SK, Joyasawal S, Forrester S, Mulhearn DC, Pegan S, Johnson ME, Mesecar AD, Kozikowski AP. Tipparaju SK, et al. Among authors: mesecar ad. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3565-9. doi: 10.1016/j.bmcl.2008.05.004. Epub 2008 May 4. Bioorg Med Chem Lett. 2008. PMID: 18499454 Free PMC article.

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