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A BioBricks Metabolic Engineering Platform for the Biosynthesis of Anthracyclinones in Streptomyces coelicolor.
Wang R, Nguyen J, Hecht J, Schwartz N, Brown KV, Ponomareva LV, Niemczura M, van Dissel D, van Wezel GP, Thorson JS, Metsä-Ketelä M, Shaaban KA, Nybo SE. Wang R, et al. Among authors: metsa ketela m. ACS Synth Biol. 2022 Dec 16;11(12):4193-4209. doi: 10.1021/acssynbio.2c00498. Epub 2022 Nov 15. ACS Synth Biol. 2022. PMID: 36378506 Free PMC article.
Oxazinomycin arrests RNA polymerase at the polythymidine sequences.
Prajapati RK, Rosenqvist P, Palmu K, Mäkinen JJ, Malinen AM, Virta P, Metsä-Ketelä M, Belogurov GA. Prajapati RK, et al. Nucleic Acids Res. 2019 Nov 4;47(19):10296-10312. doi: 10.1093/nar/gkz782. Nucleic Acids Res. 2019. PMID: 31495891 Free PMC article.
65 results