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Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer.
Bennett CN, Tomlinson CC, Michalowski AM, Chu IM, Luger D, Mittereder LR, Aprelikova O, Shou J, Piwinica-Worms H, Caplen NJ, Hollingshead MG, Green JE. Bennett CN, et al. Breast Cancer Res. 2012 Jul 19;14(4):R109. doi: 10.1186/bcr3230. Breast Cancer Res. 2012. PMID: 22812567 Free PMC article.
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.
Pérez-Guijarro E, Yang HH, Araya RE, El Meskini R, Michael HT, Vodnala SK, Marie KL, Smith C, Chin S, Lam KC, Thorkelsson A, Iacovelli AJ, Kulaga A, Fon A, Michalowski AM, Hugo W, Lo RS, Restifo NP, Sharan SK, Van Dyke T, Goldszmid RS, Weaver Ohler Z, Lee MP, Day CP, Merlino G. Pérez-Guijarro E, et al. Among authors: michalowski am. Nat Med. 2020 May;26(5):781-791. doi: 10.1038/s41591-020-0818-3. Epub 2020 Apr 13. Nat Med. 2020. PMID: 32284588 Free PMC article.
MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesis.
Cataisson C, Michalowski AM, Shibuya K, Ryscavage A, Klosterman M, Wright L, Dubois W, Liu F, Zhuang A, Rodrigues KB, Hoover S, Dwyer J, Simpson MR, Merlino G, Yuspa SH. Cataisson C, et al. Among authors: michalowski am. Sci Signal. 2016 Jun 21;9(433):ra62. doi: 10.1126/scisignal.aaf5106. Sci Signal. 2016. PMID: 27330189 Free PMC article.
Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis.
Marie KL, Sassano A, Yang HH, Michalowski AM, Michael HT, Guo T, Tsai YC, Weissman AM, Lee MP, Jenkins LM, Zaidi MR, Pérez-Guijarro E, Day CP, Ylaya K, Hewitt SM, Patel NL, Arnheiter H, Davis S, Meltzer PS, Merlino G, Mishra PJ. Marie KL, et al. Among authors: michalowski am. Nat Commun. 2020 Jan 16;11(1):333. doi: 10.1038/s41467-019-14085-2. Nat Commun. 2020. PMID: 31949145 Free PMC article.
RasGRP3 contributes to formation and maintenance of the prostate cancer phenotype.
Yang D, Kedei N, Li L, Tao J, Velasquez JF, Michalowski AM, Tóth BI, Marincsák R, Varga A, Bíró T, Yuspa SH, Blumberg PM. Yang D, et al. Among authors: michalowski am. Cancer Res. 2010 Oct 15;70(20):7905-17. doi: 10.1158/0008-5472.CAN-09-4729. Epub 2010 Sep 28. Cancer Res. 2010. PMID: 20876802 Free PMC article.
131 results