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Page 1
Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein.
Janssen K, Claes F, Van de Velde D, Wehbi VL, Houben B, Lampi Y, Nys M, Khodaparast L, Khodaparast L, Louros N, van der Kant R, Verniers J, Garcia T, Ramakers M, Konstantoulea K, Maragkou K, Duran-Romaña R, Musteanu M, Barbacid M, Scorneaux B, Beirnaert E, Schymkowitz J, Rousseau F. Janssen K, et al. Among authors: nys m. Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2214921120. doi: 10.1073/pnas.2214921120. Epub 2023 Feb 22. Proc Natl Acad Sci U S A. 2023. PMID: 36812200 Free PMC article.
The structural basis for an on-off switch controlling Gβγ-mediated inhibition of TRPM3 channels.
Behrendt M, Gruss F, Enzeroth R, Dembla S, Zhao S, Crassous PA, Mohr F, Nys M, Louros N, Gallardo R, Zorzini V, Wagner D, Economou A, Rousseau F, Schymkowitz J, Philipp SE, Rohacs T, Ulens C, Oberwinkler J. Behrendt M, et al. Among authors: nys m. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):29090-29100. doi: 10.1073/pnas.2001177117. Epub 2020 Oct 29. Proc Natl Acad Sci U S A. 2020. PMID: 33122432 Free PMC article.
Insights into the structural determinants required for high-affinity binding of chiral cyclopropane-containing ligands to α4β2-nicotinic acetylcholine receptors: an integrated approach to behaviorally active nicotinic ligands.
Zhang HK, Eaton JB, Yu LF, Nys M, Mazzolari A, van Elk R, Smit AB, Alexandrov V, Hanania T, Sabath E, Fedolak A, Brunner D, Lukas RJ, Vistoli G, Ulens C, Kozikowski AP. Zhang HK, et al. Among authors: nys m. J Med Chem. 2012 Sep 27;55(18):8028-37. doi: 10.1021/jm3008739. Epub 2012 Sep 7. J Med Chem. 2012. PMID: 22928944 Free PMC article.