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Pharmacological Targeting of AMP-Activated Protein Kinase and Opportunities for Computer-Aided Drug Design.
J Med Chem. 2016 Apr 14;59(7):2879-93. doi: 10.1021/acs.jmedchem.5b01201. Epub 2015 Nov 9.
J Med Chem. 2016.
PMID: 26510622
Review.
The recruitment of AMP-activated protein kinase to glycogen is regulated by autophosphorylation.
Oligschlaeger Y, Miglianico M, Chanda D, Scholz R, Thali RF, Tuerk R, Stapleton DI, Gooley PR, Neumann D.
Oligschlaeger Y, et al. Among authors: miglianico m.
J Biol Chem. 2015 May 1;290(18):11715-28. doi: 10.1074/jbc.M114.633271. Epub 2015 Mar 19.
J Biol Chem. 2015.
PMID: 25792737
Free PMC article.
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The interaction between AMPKβ2 and the PP1-targeting subunit R6 is dynamically regulated by intracellular glycogen content.
Oligschlaeger Y, Miglianico M, Dahlmans V, Rubio-Villena C, Chanda D, Garcia-Gimeno MA, Coumans WA, Liu Y, Voncken JW, Luiken JJ, Glatz JF, Sanz P, Neumann D.
Oligschlaeger Y, et al. Among authors: miglianico m.
Biochem J. 2016 Apr 1;473(7):937-47. doi: 10.1042/BJ20151035. Epub 2016 Feb 1.
Biochem J. 2016.
PMID: 26831516
Free article.
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Small heterodimer partner (SHP) contributes to insulin resistance in cardiomyocytes.
Rodríguez-Calvo R, Chanda D, Oligschlaeger Y, Miglianico M, Coumans WA, Barroso E, Tajes M, Luiken JJ, Glatz JF, Vázquez-Carrera M, Neumann D.
Rodríguez-Calvo R, et al. Among authors: miglianico m.
Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):541-551. doi: 10.1016/j.bbalip.2017.02.006. Epub 2017 Feb 16.
Biochim Biophys Acta Mol Cell Biol Lipids. 2017.
PMID: 28214558
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Assessment of the drugability of initial malaria infection through miniaturized sporozoite assays and high-throughput screening.
Miglianico M, Bolscher JM, Vos MW, Koolen KJM, de Bruijni M, Rajagopal DS, Chen E, Kiczun M, Gray D, Campo B, Sauerwein RW, Dechering KJ.
Miglianico M, et al.
Commun Biol. 2023 Feb 23;6(1):216. doi: 10.1038/s42003-023-04599-3.
Commun Biol. 2023.
PMID: 36823266
Free PMC article.
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NR2F2 controls malignant squamous cell carcinoma state by promoting stemness and invasion and repressing differentiation.
Mauri F, Schepkens C, Lapouge G, Drogat B, Song Y, Pastushenko I, Rorive S, Blondeau J, Golstein S, Bareche Y, Miglianico M, Nkusi E, Rozzi M, Moers V, Brisebarre A, Raphaël M, Dubois C, Allard J, Durdu B, Ribeiro F, Sotiriou C, Salmon I, Vakili J, Blanpain C.
Mauri F, et al. Among authors: miglianico m.
Nat Cancer. 2021 Nov;2(11):1152-1169. doi: 10.1038/s43018-021-00287-5. Epub 2021 Nov 22.
Nat Cancer. 2021.
PMID: 35122061
Free PMC article.
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Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases.
Miglianico M, Eldering M, Slater H, Ferguson N, Ambrose P, Lees RS, Koolen KMJ, Pruzinova K, Jancarova M, Volf P, Koenraadt CJM, Duerr HP, Trevitt G, Yang B, Chatterjee AK, Wisler J, Sturm A, Bousema T, Sauerwein RW, Schultz PG, Tremblay MS, Dechering KJ.
Miglianico M, et al.
Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6920-E6926. doi: 10.1073/pnas.1801338115. Epub 2018 Jul 2.
Proc Natl Acad Sci U S A. 2018.
PMID: 29967151
Free PMC article.
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