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Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis.
Sveidahl Johansen O, Ma T, Hansen JB, Markussen LK, Schreiber R, Reverte-Salisa L, Dong H, Christensen DP, Sun W, Gnad T, Karavaeva I, Nielsen TS, Kooijman S, Cero C, Dmytriyeva O, Shen Y, Razzoli M, O'Brien SL, Kuipers EN, Nielsen CH, Orchard W, Willemsen N, Jespersen NZ, Lundh M, Sustarsic EG, Hallgren CM, Frost M, McGonigle S, Isidor MS, Broholm C, Pedersen O, Hansen JB, Grarup N, Hansen T, Kjær A, Granneman JG, Babu MM, Calebiro D, Nielsen S, Rydén M, Soccio R, Rensen PCN, Treebak JT, Schwartz TW, Emanuelli B, Bartolomucci A, Pfeifer A, Zechner R, Scheele C, Mandrup S, Gerhart-Hines Z. Sveidahl Johansen O, et al. Among authors: frost m. Cell. 2021 Jun 24;184(13):3502-3518.e33. doi: 10.1016/j.cell.2021.04.037. Epub 2021 May 27. Cell. 2021. PMID: 34048700 Free PMC article.
NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner.
Basse AL, Nielsen KN, Karavaeva I, Ingerslev LR, Ma T, Havelund JF, Nielsen TS, Frost M, Peics J, Dalbram E, Dall M, Zierath JR, Barrès R, Færgeman NJ, Treebak JT, Gerhart-Hines Z. Basse AL, et al. Among authors: frost m. Proc Natl Acad Sci U S A. 2023 Apr 4;120(14):e2220102120. doi: 10.1073/pnas.2220102120. Epub 2023 Mar 30. Proc Natl Acad Sci U S A. 2023. PMID: 36996103 Free PMC article.
Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure.
Nicolaisen TS, Klein AB, Dmytriyeva O, Lund J, Ingerslev LR, Fritzen AM, Carl CS, Lundsgaard AM, Frost M, Ma T, Schjerling P, Gerhart-Hines Z, Flamant F, Gauthier K, Larsen S, Richter EA, Kiens B, Clemmensen C. Nicolaisen TS, et al. Among authors: frost m. FASEB J. 2020 Nov;34(11):15480-15491. doi: 10.1096/fj.202001258RR. Epub 2020 Sep 23. FASEB J. 2020. PMID: 32969079 Free PMC article.