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Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4.
Okunade GW, Miller ML, Pyne GJ, Sutliff RL, O'Connor KT, Neumann JC, Andringa A, Miller DA, Prasad V, Doetschman T, Paul RJ, Shull GE. Okunade GW, et al. Among authors: miller ml, miller da. J Biol Chem. 2004 Aug 6;279(32):33742-50. doi: 10.1074/jbc.M404628200. Epub 2004 Jun 3. J Biol Chem. 2004. PMID: 15178683 Free article.
Loss of the Atp2c1 secretory pathway Ca(2+)-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes.
Okunade GW, Miller ML, Azhar M, Andringa A, Sanford LP, Doetschman T, Prasad V, Shull GE. Okunade GW, et al. Among authors: miller ml. J Biol Chem. 2007 Sep 7;282(36):26517-27. doi: 10.1074/jbc.M703029200. Epub 2007 Jun 27. J Biol Chem. 2007. PMID: 17597066 Free article.
693 results