Miller RA - Search Results

1

Lysosomal targetomics of ghr KO mice shows chaperone-mediated autophagy degrades nucleocytosolic acetyl-coA enzymes.

Endicott SJ, Monovich AC, Huang EL, Henry EI, Boynton DN, Beckmann LJ, MacCoss MJ, Miller RA. Endicott SJ, et al. Among authors: miller ra. Autophagy. 2022 Jul;18(7):1551-1571. doi: 10.1080/15548627.2021.1990670. Epub 2021 Dec 29. Autophagy. 2022. PMID: 34704522 Free PMC article.

2

Augmented autophagy pathways and MTOR modulation in fibroblasts from long-lived mutant mice.

Wang M, Miller RA. Wang M, et al. Among authors: miller ra. Autophagy. 2012 Aug;8(8):1273-4. doi: 10.4161/auto.20917. Epub 2012 Jun 1. Autophagy. 2012. PMID: 22653655 Free PMC article.

3

mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and PAPPA-KO mice.

Dominick G, Bowman J, Li X, Miller RA, Garcia GG. Dominick G, et al. Among authors: miller ra. Aging Cell. 2017 Feb;16(1):52-60. doi: 10.1111/acel.12525. Epub 2016 Sep 13. Aging Cell. 2017. PMID: 27618784 Free PMC article.

4

Long-lived mice with reduced growth hormone signaling have a constitutive upregulation of hepatic chaperone-mediated autophagy.

Endicott SJ, Boynton DN Jr, Beckmann LJ, Miller RA. Endicott SJ, et al. Among authors: miller ra. Autophagy. 2021 Mar;17(3):612-625. doi: 10.1080/15548627.2020.1725378. Epub 2020 Feb 12. Autophagy. 2021. PMID: 32013718 Free PMC article.

5

Acarbose has sex-dependent and -independent effects on age-related physical function, cardiac health, and lipid biology.

Herrera JJ, Louzon S, Pifer K, Leander D, Merrihew GE, Park JH, Szczesniak K, Whitson J, Wilkinson JE, Fiehn O, MacCoss MJ, Day SM, Miller RA, Garratt M. Herrera JJ, et al. Among authors: miller ra. JCI Insight. 2020 Nov 5;5(21):e137474. doi: 10.1172/jci.insight.137474. JCI Insight. 2020. PMID: 32990683 Free PMC article.

6

Inhibition of class I PI3K enhances chaperone-mediated autophagy.

Endicott SJ, Ziemba ZJ, Beckmann LJ, Boynton DN, Miller RA. Endicott SJ, et al. Among authors: miller ra. J Cell Biol. 2020 Dec 7;219(12):e202001031. doi: 10.1083/jcb.202001031. J Cell Biol. 2020. PMID: 33048163 Free PMC article.

7

Regulation of mTOR complexes in long-lived growth hormone receptor knockout and Snell dwarf mice.

Shi X, Endicott SJ, Miller RA. Shi X, et al. Among authors: miller ra. Aging (Albany NY). 2022 Mar 19;14(6):2442-2461. doi: 10.18632/aging.203959. Epub 2022 Mar 19. Aging (Albany NY). 2022. PMID: 35305083 Free PMC article.

8

PTEN is both an activator and a substrate of chaperone-mediated autophagy.

Zhang KK, Burns CM, Skinner ME, Lombard DB, Miller RA, Endicott SJ. Zhang KK, et al. Among authors: miller ra. J Cell Biol. 2023 Sep 4;222(9):e202208150. doi: 10.1083/jcb.202208150. Epub 2023 Jul 7. J Cell Biol. 2023. PMID: 37418003 Free PMC article.

9

Fibroblasts from long-lived mutant mice exhibit increased autophagy and lower TOR activity after nutrient deprivation or oxidative stress.

Wang M, Miller RA. Wang M, et al. Among authors: miller ra. Aging Cell. 2012 Aug;11(4):668-74. doi: 10.1111/j.1474-9726.2012.00833.x. Epub 2012 Jun 4. Aging Cell. 2012. PMID: 22577861 Free PMC article.

10

Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons.

Cady G, Landeryou T, Garratt M, Kopchick JJ, Qi N, Garcia-Galiano D, Elias CF, Myers MG Jr, Miller RA, Sandoval DA, Sadagurski M. Cady G, et al. Among authors: miller ra. Mol Metab. 2017 Mar 16;6(5):393-405. doi: 10.1016/j.molmet.2017.03.001. eCollection 2017 May. Mol Metab. 2017. PMID: 28462074 Free PMC article.

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