Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

777 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Gi3 does not contribute to the inhibition of adenylate cyclase when stimulation of an alpha 2-adrenergic receptor causes activation of both Gi2 and Gi3.
McClue SJ, Selzer E, Freissmuth M, Milligan G. McClue SJ, et al. Among authors: milligan g. Biochem J. 1992 Jun 1;284 ( Pt 2)(Pt 2):565-8. doi: 10.1042/bj2840565. Biochem J. 1992. PMID: 1318036 Free PMC article.
Agonist occupancy of the alpha 2-C10 adrenergic receptor in a stable clone (1C) of Rat 1 fibroblasts produced by transfection of cells with genomic DNA encoding this receptor causes the activation of both of the pertussis-toxin-sensitive G-proteins Gi2 and Gi3 [Milligan …
Agonist occupancy of the alpha 2-C10 adrenergic receptor in a stable clone (1C) of Rat 1 fibroblasts produced by transfection of cells with …
Alpha 2-C10 adrenergic receptors expressed in rat 1 fibroblasts can regulate both adenylylcyclase and phospholipase D-mediated hydrolysis of phosphatidylcholine by interacting with pertussis toxin-sensitive guanine nucleotide-binding proteins.
MacNulty EE, McClue SJ, Carr IC, Jess T, Wakelam MJ, Milligan G. MacNulty EE, et al. Among authors: milligan g. J Biol Chem. 1992 Feb 5;267(4):2149-56. J Biol Chem. 1992. PMID: 1346392 Free article.
We have demonstrated recently in cells of one of these clones (1C) that the alpha 2-C10 receptor interacts directly with two distinct pertussis toxin-sensitive G-proteins, Gi2 and Gi3 (Milligan, G., Carr, C., Gould, G. W., Mullaney, I., and Lavan, B.E. …
We have demonstrated recently in cells of one of these clones (1C) that the alpha 2-C10 receptor interacts directly with two distinct pertus …
Concurrent down-regulation of IP prostanoid receptors and the alpha-subunit of the stimulatory guanine-nucleotide-binding protein (Gs) during prolonged exposure of neuroblastoma x glioma cells to prostanoid agonists. Quantification and functional implications.
Adie EJ, Mullaney I, McKenzie FR, Milligan G. Adie EJ, et al. Among authors: milligan g. Biochem J. 1992 Jul 15;285 ( Pt 2)(Pt 2):529-36. doi: 10.1042/bj2850529. Biochem J. 1992. PMID: 1379045 Free PMC article.
The remaining receptors were capable of interacting with the stimulatory G-protein (Gs) of the adenylate cyclase cascade, as saturation analysis of the binding of [3H]PGE1 indicated that they had a similar affinity for the 3H-labelled ligand, and because the specific bindi …
The remaining receptors were capable of interacting with the stimulatory G-protein (Gs) of the adenylate cyclase cascade, as saturati …
Agonist control of G-protein levels.
Milligan G, Green A. Milligan G, et al. Trends Pharmacol Sci. 1991 Jun;12(6):207-9. doi: 10.1016/0165-6147(91)90551-3. Trends Pharmacol Sci. 1991. PMID: 1646508 Review. No abstract available.
Cholera toxin impairment of opioid-mediated inhibition of adenylate cyclase in neuroblastoma x glioma hybrid cells is due to a toxin-induced decrease in opioid receptor levels.
McKenzie FR, Milligan G. McKenzie FR, et al. Among authors: milligan g. Biochem J. 1991 Apr 1;275 ( Pt 1)(Pt 1):175-81. doi: 10.1042/bj2750175. Biochem J. 1991. PMID: 1673334 Free PMC article.
Furthermore, levels of another pertussis toxin-sensitive G-protein (Go) expressed by these cells was also not lowered by cholera toxin treatment. However, as previously noted in other cells [Milligan, Unson & Wakelam (1989) Biochem. J. 262, 643-649], marked down …
Furthermore, levels of another pertussis toxin-sensitive G-protein (Go) expressed by these cells was also not lowered by cholera toxi …
777 results