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Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model.
Hirata-Fukae C, Li HF, Hoe HS, Gray AJ, Minami SS, Hamada K, Niikura T, Hua F, Tsukagoshi-Nagai H, Horikoshi-Sakuraba Y, Mughal M, Rebeck GW, LaFerla FM, Mattson MP, Iwata N, Saido TC, Klein WL, Duff KE, Aisen PS, Matsuoka Y. Hirata-Fukae C, et al. Among authors: minami ss. Brain Res. 2008 Jun 24;1216:92-103. doi: 10.1016/j.brainres.2008.03.079. Epub 2008 Apr 10. Brain Res. 2008. PMID: 18486110
BACE1 inhibition reduces endogenous Abeta and alters APP processing in wild-type mice.
Nishitomi K, Sakaguchi G, Horikoshi Y, Gray AJ, Maeda M, Hirata-Fukae C, Becker AG, Hosono M, Sakaguchi I, Minami SS, Nakajima Y, Li HF, Takeyama C, Kihara T, Ota A, Wong PC, Aisen PS, Kato A, Kinoshita N, Matsuoka Y. Nishitomi K, et al. Among authors: minami ss. J Neurochem. 2006 Dec;99(6):1555-63. doi: 10.1111/j.1471-4159.2006.04178.x. Epub 2006 Nov 2. J Neurochem. 2006. PMID: 17083447 Free article.
ApoE mimetic peptide decreases Abeta production in vitro and in vivo.
Minami SS, Cordova A, Cirrito JR, Tesoriero JA, Babus LW, Davis GC, Dakshanamurthy S, Turner RS, Pak DTs, Rebeck GW, Paige M, Hoe HS. Minami SS, et al. Mol Neurodegener. 2010 Apr 20;5:16. doi: 10.1186/1750-1326-5-16. Mol Neurodegener. 2010. PMID: 20406479 Free PMC article.
21 results