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Proteopathic tau seeding predicts tauopathy in vivo.
Holmes BB, Furman JL, Mahan TE, Yamasaki TR, Mirbaha H, Eades WC, Belaygorod L, Cairns NJ, Holtzman DM, Diamond MI. Holmes BB, et al. Among authors: mirbaha h. Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):E4376-85. doi: 10.1073/pnas.1411649111. Epub 2014 Sep 26. Proc Natl Acad Sci U S A. 2014. PMID: 25261551 Free PMC article.
A synthetic heparinoid blocks Tau aggregate cell uptake and amplification.
Stopschinski BE, Thomas TL, Nadji S, Darvish E, Fan L, Holmes BB, Modi AR, Finnell JG, Kashmer OM, Estill-Terpack S, Mirbaha H, Luu HS, Diamond MI. Stopschinski BE, et al. Among authors: mirbaha h. J Biol Chem. 2020 Mar 6;295(10):2974-2983. doi: 10.1074/jbc.RA119.010353. Epub 2020 Jan 23. J Biol Chem. 2020. PMID: 31974166 Free PMC article.
Tau seeding in cases of multiple sclerosis.
LaCroix MS, Mirbaha H, Shang P, Zandee S, Foong C, Prat A, White CL 3rd, Stuve O, Diamond MI. LaCroix MS, et al. Among authors: mirbaha h. Acta Neuropathol Commun. 2022 Oct 11;10(1):146. doi: 10.1186/s40478-022-01444-2. Acta Neuropathol Commun. 2022. PMID: 36221144 Free PMC article.
Distinct tau prion strains propagate in cells and mice and define different tauopathies.
Sanders DW, Kaufman SK, DeVos SL, Sharma AM, Mirbaha H, Li A, Barker SJ, Foley AC, Thorpe JR, Serpell LC, Miller TM, Grinberg LT, Seeley WW, Diamond MI. Sanders DW, et al. Among authors: mirbaha h. Neuron. 2014 Jun 18;82(6):1271-88. doi: 10.1016/j.neuron.2014.04.047. Epub 2014 May 22. Neuron. 2014. PMID: 24857020 Free PMC article.
17 results