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Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis.
Elwakeel E, Brüggemann M, Wagih J, Lityagina O, Elewa MAF, Han Y, Frömel T, Popp R, Nicolas AM, Schreiber Y, Gradhand E, Thomas D, Nüsing R, Steinmetz-Späh J, Savai R, Fokas E, Fleming I, Greten FR, Zarnack K, Brüne B, Weigert A. Elwakeel E, et al. Among authors: bruggemann m. Cancer Res. 2022 Apr 1;82(7):1380-1395. doi: 10.1158/0008-5472.CAN-21-2116. Cancer Res. 2022. PMID: 35105690
Poison cassette exon splicing of SRSF6 regulates nuclear speckle dispersal and the response to hypoxia.
de Oliveira Freitas Machado C, Schafranek M, Brüggemann M, Hernández Cañás MC, Keller M, Di Liddo A, Brezski A, Blümel N, Arnold B, Bremm A, Wittig I, Jaé N, McNicoll F, Dimmeler S, Zarnack K, Müller-McNicoll M. de Oliveira Freitas Machado C, et al. Among authors: bruggemann m. Nucleic Acids Res. 2023 Jan 25;51(2):870-890. doi: 10.1093/nar/gkac1225. Nucleic Acids Res. 2023. PMID: 36620874 Free PMC article.
Phenotypic Plasticity of Fibroblasts during Mammary Carcinoma Development.
Elwakeel E, Brüggemann M, Fink AF, Schulz MH, Schmid T, Savai R, Brüne B, Zarnack K, Weigert A. Elwakeel E, et al. Among authors: bruggemann m. Int J Mol Sci. 2019 Sep 9;20(18):4438. doi: 10.3390/ijms20184438. Int J Mol Sci. 2019. PMID: 31505876 Free PMC article.
The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation.
Hildebrandt A, Brüggemann M, Rücklé C, Boerner S, Heidelberger JB, Busch A, Hänel H, Voigt A, Möckel MM, Ebersberger S, Scholz A, Dold A, Schmid T, Ebersberger I, Roignant JY, Zarnack K, König J, Beli P. Hildebrandt A, et al. Among authors: bruggemann m. Genome Biol. 2019 Oct 22;20(1):216. doi: 10.1186/s13059-019-1814-0. Genome Biol. 2019. PMID: 31640799 Free PMC article.