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Feedback between p21 and reactive oxygen production is necessary for cell senescence.
Passos JF, Nelson G, Wang C, Richter T, Simillion C, Proctor CJ, Miwa S, Olijslagers S, Hallinan J, Wipat A, Saretzki G, Rudolph KL, Kirkwood TB, von Zglinicki T. Passos JF, et al. Among authors: miwa s. Mol Syst Biol. 2010;6:347. doi: 10.1038/msb.2010.5. Epub 2010 Feb 16. Mol Syst Biol. 2010. PMID: 20160708 Free PMC article.
Mitochondria are required for pro-ageing features of the senescent phenotype.
Correia-Melo C, Marques FD, Anderson R, Hewitt G, Hewitt R, Cole J, Carroll BM, Miwa S, Birch J, Merz A, Rushton MD, Charles M, Jurk D, Tait SW, Czapiewski R, Greaves L, Nelson G, Bohlooly-Y M, Rodriguez-Cuenca S, Vidal-Puig A, Mann D, Saretzki G, Quarato G, Green DR, Adams PD, von Zglinicki T, Korolchuk VI, Passos JF. Correia-Melo C, et al. Among authors: miwa s. EMBO J. 2016 Apr 1;35(7):724-42. doi: 10.15252/embj.201592862. Epub 2016 Feb 4. EMBO J. 2016. PMID: 26848154 Free PMC article.
Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?
Korolchuk VI, Miwa S, Carroll B, von Zglinicki T. Korolchuk VI, et al. Among authors: miwa s. EBioMedicine. 2017 Jul;21:7-13. doi: 10.1016/j.ebiom.2017.03.020. Epub 2017 Mar 14. EBioMedicine. 2017. PMID: 28330601 Free PMC article. Review.
The bystander effect contributes to the accumulation of senescent cells in vivo.
da Silva PFL, Ogrodnik M, Kucheryavenko O, Glibert J, Miwa S, Cameron K, Ishaq A, Saretzki G, Nagaraja-Grellscheid S, Nelson G, von Zglinicki T. da Silva PFL, et al. Among authors: miwa s. Aging Cell. 2019 Feb;18(1):e12848. doi: 10.1111/acel.12848. Epub 2018 Nov 21. Aging Cell. 2019. PMID: 30462359 Free PMC article.
Measuring reactive oxygen species in senescent cells.
Passos JF, Miwa S, von Zglinicki T. Passos JF, et al. Among authors: miwa s. Methods Mol Biol. 2013;965:253-63. doi: 10.1007/978-1-62703-239-1_17. Methods Mol Biol. 2013. PMID: 23296664
Senescence in Post-Mitotic Cells: A Driver of Aging?
von Zglinicki T, Wan T, Miwa S. von Zglinicki T, et al. Among authors: miwa s. Antioxid Redox Signal. 2021 Feb 1;34(4):308-323. doi: 10.1089/ars.2020.8048. Epub 2020 Apr 27. Antioxid Redox Signal. 2021. PMID: 32164429 Free PMC article. Review.
How good is the evidence that cellular senescence causes skin ageing?
Low E, Alimohammadiha G, Smith LA, Costello LF, Przyborski SA, von Zglinicki T, Miwa S. Low E, et al. Among authors: miwa s. Ageing Res Rev. 2021 Nov;71:101456. doi: 10.1016/j.arr.2021.101456. Epub 2021 Sep 3. Ageing Res Rev. 2021. PMID: 34487917 Free PMC article. Review.
1,219 results