Modrich P - Search Results

1

The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase.

Yang Q, Zhang R, Wang XW, Linke SP, Sengupta S, Hickson ID, Pedrazzi G, Perrera C, Stagljar I, Littman SJ, Modrich P, Harris CC. Yang Q, et al. Among authors: modrich p. Oncogene. 2004 May 6;23(21):3749-56. doi: 10.1038/sj.onc.1207462. Oncogene. 2004. PMID: 15064730

2

Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability.

Ma AH, Xia L, Littman SJ, Swinler S, Lader G, Polinkovsky A, Olechnowicz J, Kasturi L, Lutterbaugh J, Modrich P, Veigl ML, Markowitz SD, Sedwick WD. Ma AH, et al. Among authors: modrich p. Oncogene. 2000 Apr 27;19(18):2249-56. doi: 10.1038/sj.onc.1203568. Oncogene. 2000. PMID: 10822375

3

Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha.

Genschel J, Littman SJ, Drummond JT, Modrich P. Genschel J, et al. Among authors: modrich p. J Biol Chem. 1998 Jul 31;273(31):19895-901. doi: 10.1074/jbc.273.31.19895. J Biol Chem. 1998. PMID: 9677427 Free article.

Coupled with previous findings (J. T. Drummond, J. Genschel, E. Wolf, and P. Modrich (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 10144-10149), these results suggest that hMSH2 partitions between available pools of hMSH3 and hMSH6 and indicate that hMSH2 positively mo …

Coupled with previous findings (J. T. Drummond, J. Genschel, E. Wolf, and P. Modrich (1997) Proc. Natl. Acad. Sci. U. S. A. 94 …

4

Repair of large insertion/deletion heterologies in human nuclear extracts is directed by a 5' single-strand break and is independent of the mismatch repair system.

Littman SJ, Fang WH, Modrich P. Littman SJ, et al. Among authors: modrich p. J Biol Chem. 1999 Mar 12;274(11):7474-81. doi: 10.1074/jbc.274.11.7474. J Biol Chem. 1999. PMID: 10066813 Free article.

5

Increased transversions in a novel mutator colon cancer cell line.

Eshleman JR, Donover PS, Littman SJ, Swinler SE, Li GM, Lutterbaugh JD, Willson JK, Modrich P, Sedwick WD, Markowitz SD, Veigl ML. Eshleman JR, et al. Among authors: modrich p. Oncogene. 1998 Mar 5;16(9):1125-30. doi: 10.1038/sj.onc.1201629. Oncogene. 1998. PMID: 9528854

6

A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype.

Nicolaides NC, Littman SJ, Modrich P, Kinzler KW, Vogelstein B. Nicolaides NC, et al. Among authors: modrich p. Mol Cell Biol. 1998 Mar;18(3):1635-41. doi: 10.1128/MCB.18.3.1635. Mol Cell Biol. 1998. PMID: 9488480 Free PMC article.

7

Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks.

Zhao J, Jain A, Iyer RR, Modrich PL, Vasquez KM. Zhao J, et al. Nucleic Acids Res. 2009 Jul;37(13):4420-9. doi: 10.1093/nar/gkp399. Epub 2009 May 25. Nucleic Acids Res. 2009. PMID: 19468048 Free PMC article.

8

HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression.

Koshiji M, To KK, Hammer S, Kumamoto K, Harris AL, Modrich P, Huang LE. Koshiji M, et al. Among authors: modrich p. Mol Cell. 2005 Mar 18;17(6):793-803. doi: 10.1016/j.molcel.2005.02.015. Mol Cell. 2005. PMID: 15780936 Free article.

9

Analysis of the excision step in human DNA mismatch repair.

Genschel J, Modrich P. Genschel J, et al. Among authors: modrich p. Methods Enzymol. 2006;408:273-84. doi: 10.1016/S0076-6879(06)08017-7. Methods Enzymol. 2006. PMID: 16793375

10

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair.

Nimonkar AV, Ozsoy AZ, Genschel J, Modrich P, Kowalczykowski SC. Nimonkar AV, et al. Among authors: modrich p. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):16906-11. doi: 10.1073/pnas.0809380105. Epub 2008 Oct 29. Proc Natl Acad Sci U S A. 2008. PMID: 18971343 Free PMC article.

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