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A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.
Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, Berman DM, Jenuwein T, Pruitt K, Sharkis SJ, Watkins DN, Herman JG, Baylin SB. Ohm JE, et al. Among authors: mohammad hp. Nat Genet. 2007 Feb;39(2):237-42. doi: 10.1038/ng1972. Epub 2007 Jan 9. Nat Genet. 2007. PMID: 17211412 Free PMC article.
Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells.
Ohm JE, Mali P, Van Neste L, Berman DM, Liang L, Pandiyan K, Briggs KJ, Zhang W, Argani P, Simons B, Yu W, Matsui W, Van Criekinge W, Rassool FV, Zambidis E, Schuebel KE, Cope L, Yen J, Mohammad HP, Cheng L, Baylin SB. Ohm JE, et al. Among authors: mohammad hp. Cancer Res. 2010 Oct 1;70(19):7662-73. doi: 10.1158/0008-5472.CAN-10-1361. Epub 2010 Sep 14. Cancer Res. 2010. PMID: 20841480 Free PMC article.
35 results