Montgomery JA - Search Results

1

BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design.

Babu YS, Chand P, Bantia S, Kotian P, Dehghani A, El-Kattan Y, Lin TH, Hutchison TL, Elliott AJ, Parker CD, Ananth SL, Horn LL, Laver GW, Montgomery JA. Babu YS, et al. Among authors: montgomery ja. J Med Chem. 2000 Sep 21;43(19):3482-6. doi: 10.1021/jm0002679. J Med Chem. 2000. PMID: 11000002 No abstract available.

2

Structure-based design of inhibitors of purine nucleoside phosphorylase. 5. 9-Deazahypoxanthines.

Niwas S, Chand P, Pathak VP, Montgomery JA. Niwas S, et al. Among authors: montgomery ja. J Med Chem. 1994 Jul 22;37(15):2477-80. doi: 10.1021/jm00041a027. J Med Chem. 1994. PMID: 8057293

3

Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(arylmethyl) derivatives of 9-deazaguanine.

Montgomery JA, Niwas S, Rose JD, Secrist JA 3rd, Babu YS, Bugg CE, Erion MD, Guida WC, Ealick SE. Montgomery JA, et al. J Med Chem. 1993 Jan 8;36(1):55-69. doi: 10.1021/jm00053a008. J Med Chem. 1993. PMID: 8421291

4

Structure-based design of inhibitors of purine nucleoside phosphorylase. 2. 9-Alicyclic and 9-heteroalicyclic derivatives of 9-deazaguanine.

Secrist JA 3rd, Niwas S, Rose JD, Babu YS, Bugg CE, Erion MD, Guida WC, Ealick SE, Montgomery JA. Secrist JA 3rd, et al. Among authors: montgomery ja. J Med Chem. 1993 Jun 25;36(13):1847-54. doi: 10.1021/jm00065a007. J Med Chem. 1993. PMID: 8515423

5

Design and synthesis of benzoic acid derivatives as influenza neuraminidase inhibitors using structure-based drug design.

Chand P, Babu YS, Bantia S, Chu N, Cole LB, Kotian PL, Laver WG, Montgomery JA, Pathak VP, Petty SL, Shrout DP, Walsh DA, Walsh GM. Chand P, et al. Among authors: montgomery ja. J Med Chem. 1997 Dec 5;40(25):4030-52. doi: 10.1021/jm970479e. J Med Chem. 1997. PMID: 9406595

6

Potent inhibition of influenza sialidase by a benzoic acid containing a 2-pyrrolidinone substituent.

Atigadda VR, Brouillette WJ, Duarte F, Ali SM, Babu YS, Bantia S, Chand P, Chu N, Montgomery JA, Walsh DA, Sudbeck EA, Finley J, Luo M, Air GM, Laver GW. Atigadda VR, et al. Among authors: montgomery ja. J Med Chem. 1999 Jul 1;42(13):2332-43. doi: 10.1021/jm980707k. J Med Chem. 1999. PMID: 10395473

7

Hydrophobic benzoic acids as inhibitors of influenza neuraminidase.

Atigadda VR, Brouillette WJ, Duarte F, Babu YS, Bantia S, Chand P, Chu N, Montgomery JA, Walsh DA, Sudbeck E, Finley J, Air GM, Luo M, Laver GW. Atigadda VR, et al. Among authors: montgomery ja. Bioorg Med Chem. 1999 Nov;7(11):2487-97. doi: 10.1016/s0968-0896(99)00197-2. Bioorg Med Chem. 1999. PMID: 10632058

8

Comparison of the anti-influenza virus activity of RWJ-270201 with those of oseltamivir and zanamivir.

Bantia S, Parker CD, Ananth SL, Horn LL, Andries K, Chand P, Kotian PL, Dehghani A, El-Kattan Y, Lin T, Hutchison TL, Montgomery JA, Kellog DL, Babu YS. Bantia S, et al. Among authors: montgomery ja. Antimicrob Agents Chemother. 2001 Apr;45(4):1162-7. doi: 10.1128/AAC.45.4.1162-1167.2001. Antimicrob Agents Chemother. 2001. PMID: 11257030 Free PMC article.

9

Systematic structure-based design and stereoselective synthesis of novel multisubstituted cyclopentane derivatives with potent antiinfluenza activity.

Chand P, Kotian PL, Dehghani A, El-Kattan Y, Lin TH, Hutchison TL, Babu YS, Bantia S, Elliott AJ, Montgomery JA. Chand P, et al. Among authors: montgomery ja. J Med Chem. 2001 Dec 6;44(25):4379-92. doi: 10.1021/jm010277p. J Med Chem. 2001. PMID: 11728184

10

Structure-based design of inhibitors of purine nucleoside phosphorylase. 4. A study of phosphate mimics.

Guida WC, Elliott RD, Thomas HJ, Secrist JA 3rd, Babu YS, Bugg CE, Erion MD, Ealick SE, Montgomery JA. Guida WC, et al. Among authors: montgomery ja. J Med Chem. 1994 Apr 15;37(8):1109-14. doi: 10.1021/jm00034a008. J Med Chem. 1994. PMID: 8164252

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