Moreland RB - Search Results

1

Comparative pharmacology of human dopamine D(2)-like receptor stable cell lines coupled to calcium flux through Galpha(qo5).

Moreland RB, Nakane M, Donnelly-Roberts DL, Miller LN, Chang R, Uchic ME, Terranova MA, Gubbins EJ, Helfrich RJ, Namovic MT, El-Kouhen OF, Masters JN, Brioni JD. Moreland RB, et al. Biochem Pharmacol. 2004 Aug 15;68(4):761-72. doi: 10.1016/j.bcp.2004.05.019. Biochem Pharmacol. 2004. PMID: 15276084

2

A cell-based microarrayed compound screening format for identifying agonists of G-protein-coupled receptors.

Gopalakrishnan SM, Moreland RB, Kofron JL, Helfrich RJ, Gubbins E, McGowen J, Masters JN, Donnelly-Roberts D, Brioni JD, Burns DJ, Warrior U. Gopalakrishnan SM, et al. Among authors: moreland rb. Anal Biochem. 2003 Oct 15;321(2):192-201. doi: 10.1016/s0003-2697(03)00425-1. Anal Biochem. 2003. PMID: 14511684

3

Central mechanisms regulating penile erection in conscious rats: the dopaminergic systems related to the proerectile effect of apomorphine.

Hsieh GC, Hollingsworth PR, Martino B, Chang R, Terranova MA, O'Neill AB, Lynch JJ, Moreland RB, Donnelly-Roberts DL, Kolasa T, Mikusa JP, McVey JM, Marsh KC, Sullivan JP, Brioni JD. Hsieh GC, et al. Among authors: moreland rb. J Pharmacol Exp Ther. 2004 Jan;308(1):330-8. doi: 10.1124/jpet.103.057455. Epub 2003 Oct 20. J Pharmacol Exp Ther. 2004. PMID: 14569075

4

Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning.

Stewart AO, Cowart MD, Moreland RB, Latshaw SP, Matulenko MA, Bhatia PA, Wang X, Daanen JF, Nelson SL, Terranova MA, Namovic MT, Donnelly-Roberts DL, Miller LN, Nakane M, Sullivan JP, Brioni JD. Stewart AO, et al. Among authors: moreland rb. J Med Chem. 2004 Apr 22;47(9):2348-55. doi: 10.1021/jm0305669. J Med Chem. 2004. PMID: 15084133

5

Synthesis and functional activity of (2-aryl-1-piperazinyl)-N-(3-methylphenyl)acetamides: selective dopamine D4 receptor agonists.

Matulenko MA, Hakeem AA, Kolasa T, Nakane M, Terranova MA, Uchic ME, Miller LN, Chang R, Donnelly-Roberts DL, Namovic MT, Moreland RB, Brioni JD, Stewart AO. Matulenko MA, et al. Among authors: moreland rb. Bioorg Med Chem. 2004 Jul 1;12(13):3471-83. doi: 10.1016/j.bmc.2004.04.035. Bioorg Med Chem. 2004. PMID: 15186832

6

[3H] A-369508 ([2-[4-(2-cyanophenyl)-1-piperazinyl]-N-(3-methylphenyl) acetamide): an agonist radioligand selective for the dopamine D4 receptor.

Moreland RB, Terranova MA, Chang R, Uchic ME, Matulenko MA, Surber BW, Stewart AO, Brioni JD. Moreland RB, et al. Eur J Pharmacol. 2004 Aug 23;497(2):147-54. doi: 10.1016/j.ejphar.2004.06.049. Eur J Pharmacol. 2004. PMID: 15306199

7

Synthesis and activity of 2-[4-(4-[3H]-2-cyanophenyl)piperazinyl]-N-(2,4,6-[3H]3-3-methylphenyl)acetamide: a selective dopamine D4 receptor agonist and radioligand.

Matulenko MA, Surber B, Fan L, Kolasa T, Nakane M, Terranova MA, Uchic ME, Miller LN, Chang R, Donnelly-Roberts DL, Namovic MT, Moreland RB, Brioni JD, Stewart AO. Matulenko MA, et al. Among authors: moreland rb. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5095-8. doi: 10.1016/j.bmcl.2004.07.068. Bioorg Med Chem Lett. 2004. PMID: 15380206

8

Dopamine D2, but not D4, receptor agonists are emetogenic in ferrets.

Osinski MA, Uchic ME, Seifert T, Shaughnessy TK, Miller LN, Nakane M, Cox BF, Brioni JD, Moreland RB. Osinski MA, et al. Among authors: moreland rb. Pharmacol Biochem Behav. 2005 May;81(1):211-9. doi: 10.1016/j.pbb.2005.03.012. Pharmacol Biochem Behav. 2005. PMID: 15894081

9

Synthesis and evaluation of 3-aryl piperidine analogs as potent and efficacious dopamine D4 receptor agonists.

Wang X, Bhatia PA, Daanen JF, Latsaw SP, Rohde J, Kolasa T, Hakeem AA, Matulenko MA, Nakane M, Uchic ME, Miller LN, Chang R, Moreland RB, Brioni JD, Stewart AO. Wang X, et al. Among authors: moreland rb. Bioorg Med Chem. 2005 Aug 1;13(15):4667-78. doi: 10.1016/j.bmc.2005.04.060. Bioorg Med Chem. 2005. PMID: 15896964

10

A-412997 is a selective dopamine D4 receptor agonist in rats.

Moreland RB, Patel M, Hsieh GC, Wetter JM, Marsh K, Brioni JD. Moreland RB, et al. Pharmacol Biochem Behav. 2005 Sep;82(1):140-7. doi: 10.1016/j.pbb.2005.08.001. Epub 2005 Sep 8. Pharmacol Biochem Behav. 2005. PMID: 16153699

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