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A synthetically lethal nanomedicine delivering novel inhibitors of polynucleotide kinase 3'-phosphatase (PNKP) for targeted therapy of PTEN-deficient colorectal cancer.
J Control Release. 2021 Jun 10;334:335-352. doi: 10.1016/j.jconrel.2021.04.034. Epub 2021 Apr 30.
J Control Release. 2021.
PMID: 33933518
Free article.
Nanoencapsulation of Novel Inhibitors of PNKP for Selective Sensitization to Ionizing Radiation and Irinotecan and Induction of Synthetic Lethality.
Shire Z, Vakili MR, Morgan TDR, Hall DG, Lavasanifar A, Weinfeld M.
Shire Z, et al. Among authors: morgan tdr.
Mol Pharm. 2018 Jun 4;15(6):2316-2326. doi: 10.1021/acs.molpharmaceut.8b00169. Epub 2018 May 3.
Mol Pharm. 2018.
PMID: 29688721
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Scope and Mechanism of a True Organocatalytic Beckmann Rearrangement with a Boronic Acid/Perfluoropinacol System under Ambient Conditions.
Mo X, Morgan TDR, Ang HT, Hall DG.
Mo X, et al. Among authors: morgan tdr.
J Am Chem Soc. 2018 Apr 18;140(15):5264-5271. doi: 10.1021/jacs.8b01618. Epub 2018 Apr 6.
J Am Chem Soc. 2018.
PMID: 29565116
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Lewis Acid-Mediated Cyclization of Allenyl Aryl Ketones.
Zaky M, Li Z, Morgan TDR, LeFort FM, Boyd RJ, Burnell DJ.
Zaky M, et al. Among authors: morgan tdr.
J Org Chem. 2019 Nov 1;84(21):13665-13675. doi: 10.1021/acs.joc.9b01900. Epub 2019 Oct 4.
J Org Chem. 2019.
PMID: 31553185
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Nazarov reactions intercepted by (4 + 3) cycloadditions with oxygen-substituted dienes.
LeFort FM, Mishra V, Dexter GD, Morgan TD, Burnell DJ.
LeFort FM, et al.
J Org Chem. 2015 Jun 5;80(11):5877-86. doi: 10.1021/acs.joc.5b00914. Epub 2015 May 22.
J Org Chem. 2015.
PMID: 25984922
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Torquoselectivity in the Nazarov reactions of allenyl vinyl ketones.
Morgan TD, LeBlanc LM, Ardagh GH, Boyd RJ, Burnell DJ.
Morgan TD, et al.
J Org Chem. 2015 Jan 16;80(2):1042-51. doi: 10.1021/jo502532a. Epub 2015 Jan 5.
J Org Chem. 2015.
PMID: 25521250
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