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Targeting Xist with compounds that disrupt RNA structure and X inactivation.
Aguilar R, Spencer KB, Kesner B, Rizvi NF, Badmalia MD, Mrozowich T, Mortison JD, Rivera C, Smith GF, Burchard J, Dandliker PJ, Patel TR, Nickbarg EB, Lee JT. Aguilar R, et al. Among authors: mortison jd. Nature. 2022 Apr;604(7904):160-166. doi: 10.1038/s41586-022-04537-z. Epub 2022 Mar 30. Nature. 2022. PMID: 35355011
Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures.
Mortison JD, Schenone M, Myers JA, Zhang Z, Chen L, Ciarlo C, Comer E, Natchiar SK, Carr SA, Klaholz BP, Myers AG. Mortison JD, et al. Cell Chem Biol. 2018 Dec 20;25(12):1506-1518.e13. doi: 10.1016/j.chembiol.2018.09.010. Epub 2018 Oct 11. Cell Chem Biol. 2018. PMID: 30318461 Free PMC article.
A mass spectrometry-based proteome map of drug action in lung cancer cell lines.
Ruprecht B, Di Bernardo J, Wang Z, Mo X, Ursu O, Christopher M, Fernandez RB, Zheng L, Dill BD, Wang H, Xu Y, Liaw A, Mortison JD, Siriwardana N, Andresen B, Glick M, Tata JR, Kutilek V, Cornella-Taracido I, Chi A. Ruprecht B, et al. Among authors: mortison jd. Nat Chem Biol. 2020 Oct;16(10):1111-1119. doi: 10.1038/s41589-020-0572-3. Epub 2020 Jul 20. Nat Chem Biol. 2020. PMID: 32690943
Discovery and characterization of novel peptide inhibitors of the NRF2/MAFG/DNA ternary complex for the treatment of cancer.
Simov V, Altman MD, Bianchi E, DelRizzo S, DiNunzio EN, Feng G, Goldenblatt P, Ingenito R, Johnson SA, Mansueto MS, Mayhood T, Mortison JD, Serebrov V, Sondey C, Sriraman V, Tucker TJ, Walji A, Wan H, Yue Y, Stoeck A, DiMauro EF. Simov V, et al. Among authors: mortison jd. Eur J Med Chem. 2021 Nov 15;224:113686. doi: 10.1016/j.ejmech.2021.113686. Epub 2021 Jul 7. Eur J Med Chem. 2021. PMID: 34303079
Publisher Correction: A mass spectrometry-based proteome map of drug action in lung cancer cell lines.
Ruprecht B, Di Bernardo J, Wang Z, Mo X, Ursu O, Christopher M, Fernandez RB, Zheng L, Dill BD, Wang H, Xu Y, Liaw A, Mortison JD, Siriwardana N, Andresen B, Glick M, Tata JR, Kutilek V, Cornella-Taracido I, Chi A. Ruprecht B, et al. Among authors: mortison jd. Nat Chem Biol. 2020 Oct;16(10):1149. doi: 10.1038/s41589-020-0643-5. Nat Chem Biol. 2020. PMID: 32792589
12 results