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Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors.
Cai C, Chen S, Ng P, Bubley GJ, Nelson PS, Mostaghel EA, Marck B, Matsumoto AM, Simon NI, Wang H, Chen S, Balk SP. Cai C, et al. Among authors: mostaghel ea. Cancer Res. 2011 Oct 15;71(20):6503-13. doi: 10.1158/0008-5472.CAN-11-0532. Epub 2011 Aug 25. Cancer Res. 2011. PMID: 21868758 Free PMC article.
Intraprostatic steroidogenic enzymes - letter.
Mostaghel E, Nelson PS, Nelson C, Montgomery RB. Mostaghel E, et al. Cancer Res. 2010 Oct 15;70(20):8247-9; author reply 8249-50. doi: 10.1158/0008-5472.CAN-10-1458. Epub 2010 Oct 12. Cancer Res. 2010. PMID: 20940409 Free article. No abstract available.
SLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer.
Yang M, Xie W, Mostaghel E, Nakabayashi M, Werner L, Sun T, Pomerantz M, Freedman M, Ross R, Regan M, Sharifi N, Figg WD, Balk S, Brown M, Taplin ME, Oh WK, Lee GS, Kantoff PW. Yang M, et al. J Clin Oncol. 2011 Jun 20;29(18):2565-73. doi: 10.1200/JCO.2010.31.2405. Epub 2011 May 23. J Clin Oncol. 2011. PMID: 21606417 Free PMC article.
Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer.
Hu R, Lu C, Mostaghel EA, Yegnasubramanian S, Gurel M, Tannahill C, Edwards J, Isaacs WB, Nelson PS, Bluemn E, Plymate SR, Luo J. Hu R, et al. Among authors: mostaghel ea. Cancer Res. 2012 Jul 15;72(14):3457-62. doi: 10.1158/0008-5472.CAN-11-3892. Epub 2012 Jun 18. Cancer Res. 2012. PMID: 22710436 Free PMC article.
110 results